ISSN 1022-7954, Russian Journal of Genetics, 2009, Vol. 45, No. 3, pp. 335–340. © Pleiades Publishing, Inc., 2009.
Original Russian Text © I.N. Sorokina, E.V. Balanovska, M.I. Churnosov, 2009, published in Genetika, 2009, Vol. 45, No. 3, pp. 383–389.
Marriage migration parameters, including those of
Malecot’s isolation-by-distance model, are important
characteristics of population structure. Malecot’s isola-
tion-by-distance model adequately describes the struc-
ture of the modern population, and the local inbreeding
) corresponds to the population subdivision
) calculated from the data on surnames.
The possibilities of estimating both interpopulation and
intrapopulation genetic relationship and studying a
considerable number of subpopulations are important
advantages of the model [1, 2].
The approach to the estimation of inbreeding based
on Malecot’s isolation-by-distance model is widely
used in studies on the genetic structure of various pop-
ulations, including that of middle Dalmatia in the
former Yugoslavia  and modern island populations
of Bar  and other places .
Malecot’s isolation-by-distance model was used to
study the populations of Moscow , the Non-Cher-
nozem region of Russia , Kursk oblast , Marii El
[2, 9], Adygea , Ukraine , Chuvashia , etc.
In this study, we used Malecot’s isolation-by-dis-
tance model to analyze the changes in the marriage
migration characteristics of populations of southern
central Russia during the past 50 years.
MATERIALS AND METHODS
Since Belgorod oblast was established as an admin-
istrative region as recently as 1954, we studied the pop-
ulation genetic mechanisms of the formation of the new
regional population by analyzing the changes in popu-
lation parameters, with the use of Malecot’s isolation-
by-distance model, during two periods: 1947–1953
(before Belgorod oblast was established) and 1987–
2001. We studied the populations of two pairs of neigh-
boring districts: (1) Pristen’ raion (an administrative
district of Kursk oblast) and Prokhorovka raion (a dis-
trict of Kursk oblast before 1954 and a district of Bel-
gorod oblast afterwards); (2) Rep’evka raion (a district
of Voronezh oblast) and Krasnoe raion (a district of
Voronezh oblast before 1954 and a district of Belgorod
oblast afterwards) (ﬁgure).
Prokhorovka raion is located in northern Belgorod
oblast and borders on Pristen’ raion of Kursk oblast.
The district population is 27800 people. The district
comprises 19 rural municipalities. Pristen’ raion of
Kursk oblast comprises 18 rural municipalities with a
total population of 10100 people.
Krasnoe raion is located in northeastern Belgorod
oblast and borders on Rep’evka raion of Voronezh
oblast. The population of Krasnoe raion is 15500 peo-
ple. The district comprises ten rural municipalities. The
population of Rep’evka raion of Voronezh oblast, com-
prising 11 rural municipalities, is 10100 people. Note
that the administrative centers of all the districts studied
are, as a rule, the villages (rather than towns) that have
The Gene Pool of the Belgorod Oblast Population:
Malecot’s Isolation-by-Distance Parameters
I. N. Sorokina
, E. V. Balanovska
, and M. I. Churnosov
Belgorod State University, Belgorod, 308015 Russia;
Medical Genetic Research Center, Russian Academy of Medical Sciences, Moscow, 115478 Russia
Received March 19, 2007
—The mean distance between birthplaces of spouses (
), the proportion of medium migrations (
and the effective migration pressure (
) have considerably increased, and the linear systematic pressure coef-
) has decreased in the human population of the Central Chernozem region during the past 50 years.
However, the local inbreeding level (
), which is determined by both an increase in the migration intensity and
a decrease in the effective population size (
), has remained practically unchanged. A change in the regional
administrative structure has affected the genetic structure of populations. In the 1950s, raions (administrative
districts) of Kursk and Voronezh oblasts (regions) were similar with respect differentiation parameters, whereas
the oblasts considerably differed from each other. At present, some Malecot’s isolation-by-distance parameters
for the populations of the districts that were included to Belgorod oblast in 1954 are lower and similar to those
for the districts that remain in Kursk and Voronezh oblasts.