The gene encoding PRBP, the mouse homolog of human TRBP, maps to distal Chromosome 15

The gene encoding PRBP, the mouse homolog of human TRBP, maps to distal Chromosome 15 Mammalian Genome 9, Brief Data Reports 413 characteristic for the human and rat 2X isoform [10,11]. Thus, the and D15Hun17 (Fig. 1). A Prbp pseudogene maps to Chr 6, clone isolated can be considered as the porcine 2X isoform ac- band B. cording to the human classification of MYH isoforms [12]. Methods of mapping: The Prbp gene was mapped by fluorescence The porcine pAZMY9 clone was hybridized to GTG-banded in situ hybridization (FISH) and by typing 96 animals from The pig metaphase spreads. In 16 of the 18 metaphases examined, Jackson Laboratory BSS interspecific [(C57BL/6JEi x SPRET/ distinct fluorescent signals were found on both chromatids of each Ei)F 1 x SPRET/Ei] backcross panel [1]. A Prbp pseudogene was of the two homologs of Chr. 12 at the qter region (Fig. la). This mapped by FISH. high efficiency may be caused by clustering of skeletal myosin Database deposit information: The typing data have been depos- heavy chain genes [1], as reported for other species [5,7]. From the ited in the Mouse Genome Database (accession No. MGD-MRK- GTG-banded images it could be deduced that the signals were 37240) and may be obtained through the World Wide Web (http:// located at band Mammalian Genome Springer Journals

The gene encoding PRBP, the mouse homolog of human TRBP, maps to distal Chromosome 15

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Copyright © 1998 by Springer-Verlag
Life Sciences; Cell Biology; Anatomy; Zoology
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