The gastrointestinal microbiome: a malleable, third genome of mammals

The gastrointestinal microbiome: a malleable, third genome of mammals The nonpathogenic, mutualistic bacteria of the mammalian gastrointestinal tract provide a number of benefits to the host. Recent reports have shown how the aggregate genomes of gastrointestinal bacteria provide novel benefits by functioning as the third major genome in mammals along with the nuclear and mitochondrial genomes. Consequently, efforts are underway to elucidate the complexity of the organisms comprising the unique ecosystem of the gastrointestinal tract, as well as those associated with other epidermal surfaces. The current knowledge of the gastrointestinal microbiome, its relationship to human health and disease with a particular focus on mammalian physiology, and efforts to alter its composition as a novel therapeutic approach are reviewed. Mammalian Genome Springer Journals

The gastrointestinal microbiome: a malleable, third genome of mammals

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Copyright © 2009 by Springer Science+Business Media, LLC
Life Sciences; Zoology ; Anatomy ; Cell Biology
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