J. Fetal Med. (September 2017) 4:101–107 DOI 10.1007/s40556-017-0127-1 ORIGINAL ARTICLE The First Trimester Combined Screening Test in the Indian Population: Insights from a Cohort of 27,647 Pregnancies 1,2 2 2 3 • • • • K. Manikandan Aarthi Rangaraj Ponmozhi Ganesan Vaishnavi Reddy 2 3 2 2 • • • Sudarshan Suresh Sujatha M. Jagadeesh Indrani Suresh Suresh Seshadri Received: 29 November 2016 / Accepted: 29 June 2017 / Published online: 29 July 2017 Society of Fetal Medicine 2017 Abstract Keywords Trisomy 21 Down syndrome screening Objective To analyse the distribution and determinants of India First trimester combined screening test Nuchal the ﬁrst trimester screening risk for the detection of trisomy translucency Prenatal screening 21 in the population in and around Chennai, a south Indian metropolitan city. Methods A cross-sectional analysis of 27,647 singleton Introduction pregnancies that underwent the ﬁrst trimester combined screening test (FTS) was carried out. For the screen posi- According to the most recent sample registration system tive cases, karyotype reports or postnatal phenotype out- (SRS) survey ﬁgures, the birth rate of India stands at an come were available. The distribution of the various average of 21 per 1000 population . The
Journal of Fetal Medicine – Springer Journals
Published: Jul 29, 2017
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