Can J Anesth/J Can Anesth (2017) 64:947–961 DOI 10.1007/s12630-017-0917-x REVI EW ART ICLE/BRIEF RE VIEW The effects of intranasal dexmedetomidine premedication in children: a systematic review and meta-analysis ´ ´ ´ ´ Les effets d’une premedication intranasale de dexmedetomidine ´ ´ chez l’enfant : revue systematique et meta-analyse . . . Jong Hun Jun, MD, PhD Kyu Nam Kim, MD, PhD Ji Yoon Kim, MD Shin Me Song, MD Received: 9 February 2017 / Revised: 19 April 2017 / Accepted: 15 June 2017 / Published online: 21 June 2017 Canadian Anesthesiologists’ Society 2017 Abstract to 1.13; P = 0.10; I = 67%). Intranasal dexmedetomidine Purpose Intranasal dexmedetomidine premedication is a was associated with a signiﬁcantly lower incidence of newly introduced method for reducing stress and anxiety nasal irritation (RR, 0.05; 95% CI, 0.01 to 0.36; P = before general anesthesia in children. We performed a 0.003; I = 0%) and postoperative nausea and vomiting meta-analysis to identify the effects of intranasal (RR, 0.63; 95% CI, 0.40 to 0.99; P = 0.04; I = 0%) than dexmedetomidine premedication in children. other premedication treatments. It also showed Source We conducted a systematic review to ﬁnd signiﬁcantly lower systolic blood pressure (weighted
Canadian Journal of Anesthesia/Journal canadien d'anesthésie – Springer Journals
Published: Jun 21, 2017
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