The effect of candesartan on pentraxin-3 plasma levels as marker of endothelial dysfunction in patients with essential arterial hypertension

The effect of candesartan on pentraxin-3 plasma levels as marker of endothelial dysfunction in... Ir J Med Sci (2017) 186:621–629 DOI 10.1007/s11845-017-1580-5 ORIGINAL ARTICLE The effect of candesartan on pentraxin-3 plasma levels as marker of endothelial dysfunction in patients with essential arterial hypertension 1 2 1 1 2 3 • • • • • • V. Buda M. Andor C. Cristescu M. Voicu F. Cochera P. Tuduce 4 2 L. Petrescu M. C. Tomescu Received: 10 August 2016 / Accepted: 7 February 2017 / Published online: 21 February 2017 Royal Academy of Medicine in Ireland 2017 Abstract Methods A total of 365 patients were included in the Background In the last decades, the studies performed on study: 127 hypertensive patients were under treatment with the field of endothelial dysfunction confirmed the fact that candesartan, 134 patients were under treatment with other the starting point of this pathology is the inflammation. hypotensive medication (beta blockers, calcium channel Several inflammatory biomarkers had been discovered and blockers, and diuretics), both groups with controlled values studied, ones showing systemic inflammation, and others of blood pressure, and 104 were normotensive persons. being more specific biomarkers and showing the local Classical methods of assessing the endothelial function inflammation. Pentraxin-3 (PTX3) is a new inflammatory were correlated with these biochemical http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Irish Journal of Medical Science (1971 -) Springer Journals

The effect of candesartan on pentraxin-3 plasma levels as marker of endothelial dysfunction in patients with essential arterial hypertension

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Publisher
Springer London
Copyright
Copyright © 2017 by Royal Academy of Medicine in Ireland
Subject
Medicine & Public Health; Internal Medicine; General Practice / Family Medicine
ISSN
0021-1265
eISSN
1863-4362
D.O.I.
10.1007/s11845-017-1580-5
Publisher site
See Article on Publisher Site

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