The dominant mouse mutations Fused toes (Ft) and oligosyndactylism (Os) are not allelic

The dominant mouse mutations Fused toes (Ft) and oligosyndactylism (Os) are not allelic Short Communications Incorporating Mouse Genome Mammalian Genome 9, 588–589 (1998). © Springer-Verlag New York Inc. 1998 The dominant mouse mutations Fused toes (Ft) and oligosyndactylism (Os) are not allelic Ralf Lesche, Ulrich Ru ¨ ther Institut fu ¨ r Molekularbiologie, OE5250 Medizinische Hochschule Hannover, 30623 Hannover, Germany Received: 13 January 1998 / Accepted: 12 March 1998 The outgrowth of the vertebrate limb is one of the classical model ment (Gru ¨ neberg 1956) which suggests a genomic deletion to be systems to study developmental processes (for a review see Tickle the molecular cause. The comparison of both mutant phenotypes 1995). Morphogenetic mouse mutants in which limb development let us hypothesize that Ft and Os might be allelic. Genes deleted or is affected have proven useful to analyze the molecular mecha- mutated by both mutations would be good candidates to function nisms underlying this process (for a review, see Cohn and Tickle in limb development. 1996). Fused toes (Ft) is a dominant mouse mutation characterized To address the question of allelism of Ft and Os, we have by partial syndactyly of fore limbs and thymic hyperplasia. Ho- crossed Ft/+ and Os/+ mice. Fifty-nine offspring from a cross of mozygous Ft http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

The dominant mouse mutations Fused toes (Ft) and oligosyndactylism (Os) are not allelic

Loading next page...
 
/lp/springer_journal/the-dominant-mouse-mutations-fused-toes-ft-and-oligosyndactylism-os-VgisGkLWqm
Publisher
Springer-Verlag
Copyright
Copyright © 1998 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900822
Publisher site
See Article on Publisher Site

Abstract

Short Communications Incorporating Mouse Genome Mammalian Genome 9, 588–589 (1998). © Springer-Verlag New York Inc. 1998 The dominant mouse mutations Fused toes (Ft) and oligosyndactylism (Os) are not allelic Ralf Lesche, Ulrich Ru ¨ ther Institut fu ¨ r Molekularbiologie, OE5250 Medizinische Hochschule Hannover, 30623 Hannover, Germany Received: 13 January 1998 / Accepted: 12 March 1998 The outgrowth of the vertebrate limb is one of the classical model ment (Gru ¨ neberg 1956) which suggests a genomic deletion to be systems to study developmental processes (for a review see Tickle the molecular cause. The comparison of both mutant phenotypes 1995). Morphogenetic mouse mutants in which limb development let us hypothesize that Ft and Os might be allelic. Genes deleted or is affected have proven useful to analyze the molecular mecha- mutated by both mutations would be good candidates to function nisms underlying this process (for a review, see Cohn and Tickle in limb development. 1996). Fused toes (Ft) is a dominant mouse mutation characterized To address the question of allelism of Ft and Os, we have by partial syndactyly of fore limbs and thymic hyperplasia. Ho- crossed Ft/+ and Os/+ mice. Fifty-nine offspring from a cross of mozygous Ft

Journal

Mammalian GenomeSpringer Journals

Published: Jul 1, 1998

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off