Curr Trop Med Rep (2017) 4:117–126 DOI 10.1007/s40475-017-0118-2 MELIOIDOSIS AND TROPICAL BACTERIOLOGY (A TORRES, SECTION EDITOR) The Current Status of Extracellular Polymeric Substances Produced by Burkholderia pseudomallei 1 1 1 Mihnea R. Mangalea & Grace I. Borlee & Bradley R. Borlee Published online: 27 July 2017 Springer International Publishing AG 2017 Abstract Abbreviations Purpose of Review Extracellular polymeric substances (EPS) Bpc Burkholderia pseudomallei complex that are produced by Burkholderia pseudomallei consist of Bcc Burkholderia cepacia complex diverse structural components that serve equally diverse pro- tective and antigenic functions. B. pseudomallei is a sapronotic disease agent that transitions from the environment Introduction to cause severe infection in humans and animals. EPS com- ponents are proposed to play a critical role in transmission, Extracellular polymeric substances (EPS) are composed of dissemination, and protection of the bacteria in these varied extracellular polysaccharides (exopolysaccharides), capsular environments. However, many of these components remain polysaccharides (CPS), extracellular DNA (eDNA), polypep- uncharacterized, and there is a lack of consensus regarding tide adhesins, extracellular enzymes, lipids, and a variety of classification of these EPS components. polymers [1� ]. The EPS has been metaphorically described as Recent Findings Bioinformatics, mutational studies, and tran- the “house of biofilm cells,”
Current Tropical Medicine Reports – Springer Journals
Published: Jul 27, 2017
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