The complex principle of cause and effect

The complex principle of cause and effect EDITORIAL Michael J. Zellweger, MD University Hospital, Basel, Switzerland Received Apr 4, 2016; accepted Apr 4, 2016 doi:10.1007/s12350-016-0509-0 Van den Hoogen et al evaluated 525 asymptomatic See related article, pp. 1305–1311 diabetic patients using the ‘‘anatomic approach’’ (coro- nary artery calcium and coronary computed tomography angiography). Patients with a normal coronary computed tomography scan had an excellent prognosis (not taking The association between diabetes and congestive into account any perfusion data). Both the calcium score heart failure and its influence on prognosis are widely and the coronary angiography data effectively risk strat- 1-3 known and have been extensively documented. 8 ified diabetic patients without chest pain. Patients with diabetes have more extensive coronary Von Scholten et al evaluated the functional and struc- artery disease, lower left ventricular ejection fraction, tural aspects of atherosclerosis in asymptomatic patients and congestive heart failure than non-diabetic patients. 9 with type 2 diabetes. These patients who were free of overt Rubler et al first described ‘‘diabetic cardiomy- cardiovascular disease had a high prevalence of coronary opathy’’ in 1972 based on four adult diabetic patients microvascular dysfunction, especially with concomitant with congestive heart failure that could not be explained albuminuria, suggesting a common microvascular impair- Journal of Nuclear Cardiology Springer Journals

The complex principle of cause and effect

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Springer US
Copyright © 2016 by American Society of Nuclear Cardiology
Medicine & Public Health; Cardiology; Nuclear Medicine; Imaging / Radiology
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