A burn is a devastating phenomenon, especially in the developing countries. A bulk amount of medical resources is required to fulfill the demand of burned patients. So, it is very important to find another alternative for the treatment of burned patients. Recently, human amniotic membrane (AM) and Moringa oleifera (MO) are being used separately to treat wounds and burn. In this study, we tried to use a mix of AM and MO formulated to a gel with sodium carboxymethylcellulose (CMC-Na), propylparaben, glycerin, distilled water, and triethanolamine and applied on the burned skin of Wistar rats. Second-degree burns were created using pieces of aluminum (2.5-cm diameter). Skin irritation study, physiological properties, the percentage of wound contraction, and epithelialization period were measured for all groups. AM+MO-treated group had maximum average body weight, food intake, and water intake. At day 24, AM+MO group showed a greater response (p < 0.00003667) than other groups. For complete epithelialization, AM+MO required only 19.6 days while AM, MO, and control group needed 23.2, 28.2, and 31.4 days, respectively. These results suggested that the combined composition of AM+MO may be used as a good therapeutic agent to treat burn and wound. Lay Summary Since burn injury is
Regenerative Engineering and Translational Medicine – Springer Journals
Published: Jun 4, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera