The canine copper toxicosis locus is not syntenic with ATP7B or ATX1 and maps to a region showing homology to human 2p21

The canine copper toxicosis locus is not syntenic with ATP7B or ATX1 and maps to a region showing... Mammalian Genome 10, 753–756 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 The canine copper toxicosis locus is not syntenic with ATP7B or ATX1 and maps to a region showing homology to human 2p21 1,2 1 2 1,2 1,2 Susan L. Dagenais, Maria Guevara-Fujita, Rob Loechel, Ann C. Burgess, Diane E. Miller, 3 2 1,2 Vilma Yuzbasiyan-Gurkan, George J. Brewer, Thomas W. Glover Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA Department of Human Genetics, 4708 Med. Sci. II, Box 0618, 1137 E. Catherine St. University of Michigan, Ann Arbor, Michigan 48109, USA Department of Molecular Medicine, College of Veterinary Medicine, Michigan State University, E. Lansing, Michigan 48824, USA Received: 1 February 1999 / Accepted: 8 March 1999 Canine copper toxicosis (CT) is an autosomal recessive disorder bination fraction of zero. This polymorphic marker has been suc- resulting in accumulation of copper at toxic levels in the liver cessfully applied in molecular diagnostic tests for CT in Bedling- owing to deficient excretion via the bile (Hardy et al. 1975). This ton terriers (Holmes et al. 1998; Ubbink et al. 1998). In an earlier disorder is prevalent in certain breeds, most notably the American study http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

The canine copper toxicosis locus is not syntenic with ATP7B or ATX1 and maps to a region showing homology to human 2p21

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Publisher
Springer-Verlag
Copyright
Copyright © 1999 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359901085
Publisher site
See Article on Publisher Site

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