The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche

The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche Curr Stem Cell Rep (2017) 3:156–163 DOI 10.1007/s40778-017-0085-5 IN VITRO AND IN VIVO MODELS IN STEM CELL BIOLOGY (E SCOTT, SECTION EDITOR) The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche 1 1 1 Negar Seyedhassantehrani & Takayoshi Otsuka & Shambhavi Singh & David M. Gardiner Published online: 27 July 2017 Springer International Publishing AG 2017 Abstract bioinspired, biomimetic materials to create a dynamic stem Purpose of Review Recent advances in genomics and gene cell niche for regeneration and scar-free repair. editing have expanded the range of model organisms to in- . . clude those with interesting biological capabilities such as Keywords Axolotl Regeneration Regenerative . . . regeneration. Among these are the classic models of regener- engineering Hyaluronic acid Heparan sulfate ECM ation biology, the salamander. Although stimulating endoge- nous regeneration in humans likely is many years away, with advances in stem cell biology and biomedical engineering Introduction (e.g., bio-inspired materials), it is evident that there is great potential to enhance regenerative outcomes by approaching Historically, model systems for studying developmental biology the problem from an engineering perspective. The question were limited to organisms with amenable genetics. These ani- at this point http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Stem Cell Reports Springer Journals

The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche

Loading next page...
 
/lp/springer_journal/the-axolotl-limb-regeneration-model-as-a-discovery-tool-for-5g1EXBAIJL
Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing AG
Subject
Life Sciences; Cell Biology; Stem Cells
eISSN
2198-7866
D.O.I.
10.1007/s40778-017-0085-5
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial