The antipsychotic agent quetiapine is increasingly not used as such: dispensed prescriptions in Norway 2004–2015

The antipsychotic agent quetiapine is increasingly not used as such: dispensed prescriptions in... Eur J Clin Pharmacol (2017) 73:1173–1179 DOI 10.1007/s00228-017-2281-8 PHARMACOEPIDEMIOLOGY AND PRESCRIPTION The antipsychotic agent quetiapine is increasingly not used as such: dispensed prescriptions in Norway 2004–2015 1 2 3 4,5 Pål Gjerden & Jørgen G. Bramness & Ingunn Fride Tvete & Lars Slørdal Received: 26 January 2017 /Accepted: 7 June 2017 /Published online: 16 June 2017 Springer-Verlag GmbH Germany 2017 Abstract treatment of a major psychiatric disorder and only 2.6% of the Purpose The antipsychotic agent quetiapine was introduced patients were prescribed 1 DDD or more per day and reim- in Norway in 2003. We have assessed changes in dispensed bursed in accordance with the drug’s primary indication, psy- prescriptions, including dosing, of quetiapine in Norway from chosis. A reported diagnosis of psychosis was not associated 2004 to 2015. with higher quetiapine doses. Methods Data on the sales of antipsychotics and antidepres- Conclusions In 2015, the pattern of quetiapine dispensing in sants were drawn from the Norwegian Prescription Database. Norway most likely reflects predominant off-label use. This is A total of 47,474 outpatients filled 195,622 prescriptions of unsettling considering poorly documented effects in non- quetiapine. Reimbursement codes, use of antipsychotics or psychotic disorders, profound side effects, significant toxicity antidepressants http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Clinical Pharmacology Springer Journals

The antipsychotic agent quetiapine is increasingly not used as such: dispensed prescriptions in Norway 2004–2015

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Biomedicine; Pharmacology/Toxicology
ISSN
0031-6970
eISSN
1432-1041
D.O.I.
10.1007/s00228-017-2281-8
Publisher site
See Article on Publisher Site

Abstract

Eur J Clin Pharmacol (2017) 73:1173–1179 DOI 10.1007/s00228-017-2281-8 PHARMACOEPIDEMIOLOGY AND PRESCRIPTION The antipsychotic agent quetiapine is increasingly not used as such: dispensed prescriptions in Norway 2004–2015 1 2 3 4,5 Pål Gjerden & Jørgen G. Bramness & Ingunn Fride Tvete & Lars Slørdal Received: 26 January 2017 /Accepted: 7 June 2017 /Published online: 16 June 2017 Springer-Verlag GmbH Germany 2017 Abstract treatment of a major psychiatric disorder and only 2.6% of the Purpose The antipsychotic agent quetiapine was introduced patients were prescribed 1 DDD or more per day and reim- in Norway in 2003. We have assessed changes in dispensed bursed in accordance with the drug’s primary indication, psy- prescriptions, including dosing, of quetiapine in Norway from chosis. A reported diagnosis of psychosis was not associated 2004 to 2015. with higher quetiapine doses. Methods Data on the sales of antipsychotics and antidepres- Conclusions In 2015, the pattern of quetiapine dispensing in sants were drawn from the Norwegian Prescription Database. Norway most likely reflects predominant off-label use. This is A total of 47,474 outpatients filled 195,622 prescriptions of unsettling considering poorly documented effects in non- quetiapine. Reimbursement codes, use of antipsychotics or psychotic disorders, profound side effects, significant toxicity antidepressants

Journal

European Journal of Clinical PharmacologySpringer Journals

Published: Jun 16, 2017

References

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