J Interv Card Electrophysiol (2017) 49:237–244 DOI 10.1007/s10840-017-0274-2 The anticoagulant effect of heparin during radiofrequency ablation (RFA) in patients taking apixaban or rivaroxaban 1 1 1 1 1 1 L. C. Brendel & F. Dobler & G. Hessling & J. Michel & S. L. Braun & A. L. Steinsiek & 1 1 1 2 2 1 1 P. Groha & R. Eckl & I. Deisenhofer & A. Hyseni & M. Roest & I. Ott & B. Steppich Received: 10 December 2016 /Accepted: 10 July 2017 /Published online: 22 July 2017 Springer Science+Business Media, LLC 2017 Abstract Precaution is necessary when monitoring periprocedural he- Purpose Measuring the anticoagulant effect of heparin during mostasis in DOAC patients to avoid mismanagement. radiofrequency ablation (RFA) in patients taking apixaban and . . . rivaroxaban is challenging, since the activated coagulation Keywords Atrial fibrillation DOACs Heparin time (ACT) does not seem to reflect the true anticoagulant Radiofrequency ablation FXa activity activity of these drugs. We therefore evaluated coagulation properties of apixaban and rivaroxaban during RFA by differ- ent coagulation assays to better monitor periprocedural 1 Introduction hemostasis. Methods The study included 90 patients (61 ± 12 years) with Due to their favorable bleeding profile,
Journal of Interventional Cardiac Electrophysiology – Springer Journals
Published: Jul 22, 2017
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