Eur J Nutr (2018) 57:179–190 https://doi.org/10.1007/s00394-016-1307-9 ORIGINAL CONTRIBUTION The amount and types of fatty acids acutely affect insulin, glycemic and gastrointestinal peptide responses but not satiety in metabolic syndrome subjects 1 1 2 Chee‑Yan Chang · M. S. Kanthimathi · Alexander Tong‑Boon Tan · 3 3 Kalanithi Nesaretnam · Kim‑Tiu Teng Received: 22 April 2016 / Accepted: 31 August 2016 / Published online: 8 September 2016 © Springer-Verlag Berlin Heidelberg 2016 Abstract acids (P < 0.001). Interestingly, incremental area under the Purpose Limited clinical evidence is available on the curve (AUC ) for glucagon-like peptide-1 was higher 0-120min effects of amount and types of dietary fats on postpran- after SUCR meal compared with MUFA (27 %) and n-6 dial insulinemic and gastrointestinal peptide responses in PUFA meals (23 %) (P = 0.01). AUC for glucose- 0-120min metabolic syndrome subjects. We hypothesized that meals dependent insulinotropic polypeptide was higher after SFA enriched with designated: (1) amount of fats (50 vs 20 g), meal compared with MUFA (23 %) and n-6 PUFA meals (2) fats with differing fatty acid composition (saturated, (20 %) (P = 0.004). Significant meal x time interaction ( P SFA; monounsaturated, MUFA or n-6 polyunsaturated fatty =
European Journal of Nutrition – Springer Journals
Published: Sep 8, 2016
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