Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the... Psychopharmacology (2017) 234:2399–2407 DOI 10.1007/s00213-017-4627-4 ORIGINAL INVESTIGATION Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats 1 2 3 1 Jasjot Saund & Daniel Dautan & Claire Rostron & Gonzalo P. Urcelay & Todor V. Gerdjikov Received: 28 July 2016 /Accepted: 7 April 2017 /Published online: 28 April 2017 The Author(s) 2017. This article is an open access publication Abstract responses or response accuracy, even under increased atten- Rationale Corticostriatal circuits are widely implicated in the tional load. Control experiments showed no effects on loco- top-down control of attention including inhibitory control and motor activity in an open field. behavioural flexibility. However, recent neurophysiological Conclusions These results complement previous lesion work evidence also suggests a role for thalamic inputs to striatum in which the DMS and orbitofrontal cortex were similarly in behaviours related to salient, reward-paired cues. implicated in perseverative responses and suggest a specific Objectives Here, we used designer receptors exclusively acti- role for thalamostriatal inputs in inhibitory control. vated by designer drugs (DREADDs) to investigate the role of . . parafascicular (Pf) thalamic inputs to the dorsomedial striatum Keywords Thalamostriatal pathway Dorsomedial striatum (DMS) using the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychopharmacology Springer Journals

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats

Loading next page...
 
/lp/springer_journal/thalamic-inputs-to-dorsomedial-striatum-are-involved-in-inhibitory-H6Qyt6LcbF
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by The Author(s)
Subject
Biomedicine; Neurosciences; Pharmacology/Toxicology; Psychiatry
ISSN
0033-3158
eISSN
1432-2072
D.O.I.
10.1007/s00213-017-4627-4
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial