Target trial emulation: teaching epidemiology and beyond

Target trial emulation: teaching epidemiology and beyond Eur J Epidemiol (2017) 32:473–475 DOI 10.1007/s10654-017-0293-4 COMMENTARY 1 1 Jeremy A. Labrecque Sonja A. Swanson Received: 22 July 2017 / Accepted: 27 July 2017 / Published online: 2 August 2017 The Author(s) 2017. This article is an open access publication Observational epidemiology is continually held to the well-specified target trial and show how common analytic standard of randomized trials. A typical epidemiology approaches would be inappropriate. article references previous trials in the introduction (or Indeed, as others have also highlighted (e.g., [1–5]), reasons why trials are not feasible) and, when possible, emulating a target trial (and the formal causal frameworks compares the results to previous trials in the discussion. it is compatible with) can help researchers identify and When the results from an observational study and trial avoid unnecessary biases and provide a clear means for disagree, we nearly always begin by questioning the for- articulating the tradeoffs we may need to make in our mer. Curiously, the methods section of an observational observational studies. Unfortunately, we cannot always study—an undeniably crucial part of an article—rarely emulate the core elements of an ideal trial: it is usually not references trial methods or designs. Explicit target trial possible to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Epidemiology Springer Journals

Target trial emulation: teaching epidemiology and beyond

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Publisher
Springer Netherlands
Copyright
Copyright © 2017 by The Author(s)
Subject
Medicine & Public Health; Epidemiology; Public Health; Infectious Diseases; Cardiology; Oncology
ISSN
0393-2990
eISSN
1573-7284
D.O.I.
10.1007/s10654-017-0293-4
Publisher site
See Article on Publisher Site

Abstract

Eur J Epidemiol (2017) 32:473–475 DOI 10.1007/s10654-017-0293-4 COMMENTARY 1 1 Jeremy A. Labrecque Sonja A. Swanson Received: 22 July 2017 / Accepted: 27 July 2017 / Published online: 2 August 2017 The Author(s) 2017. This article is an open access publication Observational epidemiology is continually held to the well-specified target trial and show how common analytic standard of randomized trials. A typical epidemiology approaches would be inappropriate. article references previous trials in the introduction (or Indeed, as others have also highlighted (e.g., [1–5]), reasons why trials are not feasible) and, when possible, emulating a target trial (and the formal causal frameworks compares the results to previous trials in the discussion. it is compatible with) can help researchers identify and When the results from an observational study and trial avoid unnecessary biases and provide a clear means for disagree, we nearly always begin by questioning the for- articulating the tradeoffs we may need to make in our mer. Curiously, the methods section of an observational observational studies. Unfortunately, we cannot always study—an undeniably crucial part of an article—rarely emulate the core elements of an ideal trial: it is usually not references trial methods or designs. Explicit target trial possible to

Journal

European Journal of EpidemiologySpringer Journals

Published: Aug 2, 2017

References

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