Synthesis, photoluminescent behaviors, and antibacterial activities of 3-acetylcoumarins

Synthesis, photoluminescent behaviors, and antibacterial activities of 3-acetylcoumarins Nine 3-acetylcoumarins derivatives were synthesized and characterized via MS, 1H NMR, FT-IR, and UV–vis absorption spectra. The fluorescence behaviors of the compounds in dichloromethane solutions were observed. The minimum inhibitory concentration was observed for the nine title compounds and antibiotics, to evaluate their in vitro antibacterial activity against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), Escherichia coli (E. Coli ATCC 25922), and extended spectrum β lactamases E. coli (ESBLs-E. coli ATCC 35218). These results showed that the compound 2 exhibits the antibacterial activities to S. aureus. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Synthesis, photoluminescent behaviors, and antibacterial activities of 3-acetylcoumarins

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Publisher
Springer Netherlands
Copyright
Copyright © 2013 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-013-1432-5
Publisher site
See Article on Publisher Site

Abstract

Nine 3-acetylcoumarins derivatives were synthesized and characterized via MS, 1H NMR, FT-IR, and UV–vis absorption spectra. The fluorescence behaviors of the compounds in dichloromethane solutions were observed. The minimum inhibitory concentration was observed for the nine title compounds and antibiotics, to evaluate their in vitro antibacterial activity against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), Escherichia coli (E. Coli ATCC 25922), and extended spectrum β lactamases E. coli (ESBLs-E. coli ATCC 35218). These results showed that the compound 2 exhibits the antibacterial activities to S. aureus.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Oct 22, 2013

References

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