Synthesis of trisubstituted furans via Ag-catalyzed cascade heterocyclization of 2-(1-alkynyl)-2-alken-1-ones with aryl-amines

Synthesis of trisubstituted furans via Ag-catalyzed cascade heterocyclization of... 2015). Generally, silver complexes are considered to have similar efficiency compared with other late transition metal catalysts and recent studies have shown that silver species exhibited interesting catalytic activities for C–C, C–N, C– O, C–P, C–S bond formation (Liu et al. 2015; Hu et al. 2014; Wang et al. 2014; Ji et al. 2009; Hu et al. 2017). Polysubstituted furans, which is one of the most important heterocyclic compounds, are not only key structural units in natural products and pharmaceuticals (Keay and Dibble 1996; Meegan 1984; Nakanishi 1974) but also useful intermediates in total syntheses (Wong et al. Keywords Silver catalyzed  Trisubstituted furans  1999; Lee et al. 2005). Many efforts have been made to Cascade reaction  Cyclization  Aryl-amine obtain furan derivatives. (Blanc et al. 2016; Gulevich et al. 2013) Transition metal-catalyzed cyclization of 2-(1-alky- nyl)-2-alken-1-ones with nucleophiles is one of the typical approaches to obtain polysubstituted furans since Larock (Yao et al. 2004) and co-works first report in 2004. Electronic supplementary material The online version of this Although the cyclization of 2-(1-alkynyl)-2-alken-1-ones article (doi:10.1007/s11696-017-0323-4) contains supplementary with alcohols (Yao et al. 2004, 2005; Patil et al. 2005), material, which is available to authorized users. nitrones http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chemical Papers Springer Journals

Synthesis of trisubstituted furans via Ag-catalyzed cascade heterocyclization of 2-(1-alkynyl)-2-alken-1-ones with aryl-amines

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Institute of Chemistry, Slovak Academy of Sciences
Subject
Chemistry; Chemistry/Food Science, general; Industrial Chemistry/Chemical Engineering; Biochemistry, general; Medicinal Chemistry; Materials Science, general; Biotechnology
ISSN
0366-6352
eISSN
1336-9075
D.O.I.
10.1007/s11696-017-0323-4
Publisher site
See Article on Publisher Site

Abstract

2015). Generally, silver complexes are considered to have similar efficiency compared with other late transition metal catalysts and recent studies have shown that silver species exhibited interesting catalytic activities for C–C, C–N, C– O, C–P, C–S bond formation (Liu et al. 2015; Hu et al. 2014; Wang et al. 2014; Ji et al. 2009; Hu et al. 2017). Polysubstituted furans, which is one of the most important heterocyclic compounds, are not only key structural units in natural products and pharmaceuticals (Keay and Dibble 1996; Meegan 1984; Nakanishi 1974) but also useful intermediates in total syntheses (Wong et al. Keywords Silver catalyzed  Trisubstituted furans  1999; Lee et al. 2005). Many efforts have been made to Cascade reaction  Cyclization  Aryl-amine obtain furan derivatives. (Blanc et al. 2016; Gulevich et al. 2013) Transition metal-catalyzed cyclization of 2-(1-alky- nyl)-2-alken-1-ones with nucleophiles is one of the typical approaches to obtain polysubstituted furans since Larock (Yao et al. 2004) and co-works first report in 2004. Electronic supplementary material The online version of this Although the cyclization of 2-(1-alkynyl)-2-alken-1-ones article (doi:10.1007/s11696-017-0323-4) contains supplementary with alcohols (Yao et al. 2004, 2005; Patil et al. 2005), material, which is available to authorized users. nitrones

Journal

Chemical PapersSpringer Journals

Published: Oct 19, 2017

References

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