MCM-41 nanostructured was prepared via simple and versatile procedure and directly immobilized with a new type of Cu–serine complex. After characterization of this catalyst, the catalytic activity of this nanostructure compound has been investigated for the synthesis of polyhydroquinoline, 2,3-dihydroquinazolin-4(1H)-one, sulfide and sulfoxide derivatives. * Mohammad Ghadermazi email@example.com * Arash Ghorbani-Choghamarani firstname.lastname@example.org; email@example.com Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj, Iran Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran Vol.:(0123456789) 1 3 858 T. Tamoradi et al. Keyword MCM-41 · Copper · Polyhydroquinoline · 2,3-Dihydroquinazolin-4(1H)-one · Sulfide · Sulfoxide ring molecules-containing organic molecules are very well- 1 Introduction known; particularly, polyhydroquinoline (PHQ) derivatives have been employed as imperative molecules in biological Diaryl sulfides and their derivatives have been intensively and pharmaceutical such as vasodilator, hepatoprotective, investigated in recent years. They have been attracting much antiatherosclerotic, bronchodilator, antitumor, geroprotec- attention, due to their wide applications in areas such as tive, antidiabetic activity and also their ability to modulate biological and pharmaceutical systems and organic synthe- calcium channels [20–25]. As reported in several well- sis. More importantly, they have found widespread applica- documented reviews, 2,3-dihydroquinazolin-4(1H)-one tion as precursors or synthetic intermediates in numerous derivatives can seek the opportunities in an important class drugs such as
Catalysis Letters – Springer Journals
Published: Feb 2, 2018
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