Access the full text.
Sign up today, get DeepDyve free for 14 days.
Matthieu Beaupérin, A. Job, H. Cattey, S. Royer, P. Meunier, Jean‐Cyrille Hierso (2010)
Copper(I) Iodide Polyphosphine Adducts at Low Loading for Sonogashira Alkynylation of Demanding Halide Substrates: Ligand Exchange Study between Copper and PalladiumOrganometallics, 29
G. Hilt, C. Hengst, Marion Arndt (2009)
The Unprecedented Cobalt-CatalysedOxidative Glaser Coupling under Reductive ConditionsSynthesis, 2009
Wen-bin Yi, C. Cai, Xin Wang (2007)
A Palladium/Perfluoroalkylated Pyridine Catalyst for Sonogashira Reaction of Aryl Bromides and Chlorides in a Fluorous Biphasic SystemEuropean Journal of Organic Chemistry, 2007
V. Hikawczuk, J. Saad, O. Giordano, Celina García, T. Martín, V. Martín, M. Sosa, C. Tonn (2008)
Insect growth regulatory effects of linear diterpenoids and derivatives from Baccharis thymifolia.Journal of natural products, 71 2
Jianxiao Li, Hao-Ran Liang, Zhao‐Yang Wang, Jian-Hua Fu (2011)
3,4-Dihalo-2(5H)-furanones: a novel oxidant for the Glaser coupling reactionMonatshefte für Chemie - Chemical Monthly, 142
S. Werner, P. Iyer, M. Fodor, Claire Coleman, Leslie Twining, Branko Mitasev, K. Brummond (2006)
Solution-phase synthesis of a tricyclic pyrrole-2-carboxamide discovery library applying a stetter-Paal-Knorr reaction sequence.Journal of combinatorial chemistry, 8 3
Yang-Qing Mo, Zhao‐Yang Wang, Wenjie Mei, Jian-Hua Fu, Yue-He Tan, Shi-He Luo (2012)
Reaction of 5-alkoxy-3,4-dihalo-2(5H)-furanones with secondary amines: expected versus unanticipated products and their preliminary bioactivity investigationsMonatshefte für Chemie - Chemical Monthly, 143
Chenchen Ma, Zhaopeng Liu, Hualong Song, Rentao Jiang, Fawen He, Shutao Ma (2010)
Synthesis and antibacterial activity of novel 11,12-cyclic carbonate azithromycin 4″-O-carbamate derivativesThe Journal of Antibiotics, 63
Xu Meng, Chuanbin Li, Baochun Han, Tiansheng Wang, Baohua Chen (2010)
Iron/copper promoted oxidative homo-coupling reaction of terminal alkynes using air as the oxidantTetrahedron, 66
Jinqiang Zhang, J. Kemmink, D. Rijkers, R. Liskamp (2011)
Cu(I)- and Ru(II)-mediated "click" cyclization of tripeptides toward vancomycin-inspired mimics.Organic letters, 13 13
S. Mecklenburg, S. Shaaban, L. Ba, Torsten Burkholz, T. Schneider, B. Diesel, A. Kiemer, Anne Röseler, K. Becker, J. Reichrath, A. Stark, W. Tilgen, M. Abbas, L. Wessjohann, F. Sasse, C. Jacob (2009)
Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing multifunctional redox agents.Organic & biomolecular chemistry, 7 22
I. Carvalho, P. Andrade, V. Campo, P. Guedes, R. Sesti-Costa, J. Silva, S. Schenkman, S. Dedola, L. Hill, M. Rejžek, S. Nepogodiev, R. Field (2010)
'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase.Bioorganic & medicinal chemistry, 18 7
L. Loeffler, Z. Sajadi, I. Hall (1977)
Antineoplastic agents. 1. N-Protected vinyl, 1,2-dihaloethyl, and cyanomethyl esters of phenylalanine.Journal of medicinal chemistry, 20 12
A. Katritzky, Qiyin Chen, S. Tala (2009)
Convenient and Efficient Preparations of Azodye‐Labeled PeptidesChemical Biology & Drug Design, 73
L. Zani, S. Alesi, P. Cozzi, C. Bolm (2006)
Dimethylzinc-mediated alkynylation of imines.The Journal of organic chemistry, 71 4
Sugata Roy, S. Singh (2005)
Liquid chromatographic method for the micro-quantitative determination of clodinafop in soil, wheat and Phalaris minor.Journal of chromatography. A, 1065 2
V. Haridas, Kashmiri Lal, Yogesh Sharma, S. Upreti (2008)
Design, synthesis, and self-assembling properties of novel triazolophanes.Organic letters, 10 8
M. Guerrero, M. Aquino, I. Bruno, M. Terencio, M. Payá, R. Riccio, L. Gomez‐Paloma (2007)
Synthesis and pharmacological evaluation of a selected library of new potential anti-inflammatory agents bearing the gamma-hydroxybutenolide scaffold: a new class of inhibitors of prostanoid production through the selective modulation of microsomal prostaglandin E synthase-1 expression.Journal of medicinal chemistry, 50 9
Taeho Lee, M. Cho, S. Ko, Hyun-Jun Youn, D. Baek, W. Cho, Chang-Yuil Kang, Sanghee Kim (2007)
Synthesis and Evaluation of 1,2,3-Triazole Containing Analogues of the Immunostimulant α-GalCerJournal of Medicinal Chemistry, 50
S. Samai, G. Nandi, M. Singh (2010)
An efficient and facile one-pot synthesis of propargylamines by three-component coupling of aldehydes, amines, and alkynes via C–H activation catalyzed by NiCl2Tetrahedron Letters, 51
Yuan Luo, B. Knuckley, M. Bhatia, P. Pellechia, P. Thompson (2006)
Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe.Journal of the American Chemical Society, 128 45
Scott Loethen, T. Ooya, H. Choi, N. Yui, D. Thompson (2006)
Synthesis, characterization, and pH-triggered dethreading of alpha-cyclodextrin-poly(ethylene glycol) polyrotaxanes bearing cleavable endcaps.Biomacromolecules, 7 9
S. Bew, Glyn Hiatt-Gipson (2010)
Synthesis of C-propargylic esters of N-protected amino acids and peptides.The Journal of organic chemistry, 75 11
Xiangmin Li, Ming Zhao, Yu-Rong Tang, Chao Wang, Ziding Zhang, Shiqi Peng (2008)
N-[2-(5,5-dimethyl-1,3-dioxane-2-yl)ethyl]amino acids: their synthesis, anti-inflammatory evaluation and QSAR analysis.European journal of medicinal chemistry, 43 1
S. Pimentel-Elardo, Svitlana Kozytska, T. Bugni, C. Ireland, H. Moll, U. Hentschel (2010)
Anti-Parasitic Compounds from Streptomyces sp. Strains Isolated from Mediterranean SpongesMarine Drugs, 8
E. Lattmann, S. Dunn, S. Niamsanit, N. Sattayasai (2005)
Synthesis and antibacterial activities of 5-hydroxy-4-amino-2(5H)-furanones.Bioorganic & medicinal chemistry letters, 15 4
X. Tian, A. Switzer, S. DeRose, R. Mishra, M. Solinsky, R. Mumin, F. Ebetino, L. Jayasinghe, M. Webster, A. Colson, D. Crossdoersen, Beth Pinney, Julie Farmer, M. Dowty, C. Obringer, C. Cruze, Melissa Burklow, P. Suchanek, Lily Dong, M. Dirr, R. Sheldon, J. Wos (2008)
Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.Journal of medicinal chemistry, 51 19
Benjamin Sauer, J. Gilbert, J. Sakoff, A. McCluskey (2009)
Synthesis of 4-substituted-3-hydroxy-5-oxo-10-oxa-4-azatricyclo[5.2.1]dec- 3-yl Acetic Acid Ethyl Esters as Norcantharidin AnaloguesLetters in Drug Design & Discovery, 6
Chunhua Liu, Xianfeng Gu, Y. Zhu (2010)
Synthesis and biological evaluation of novel leonurine-SPRC conjugate as cardioprotective agents.Bioorganic & medicinal chemistry letters, 20 23
Riccardo Surmont, G. Verniest, N. Kimpe* (2010)
Short synthesis of the seed germination inhibitor 3,4,5-trimethyl-2(5H)-furanone.The Journal of organic chemistry, 75 16
E. Lattmann, N. Sattayasai, Carl Schwalbe, S. Niamsanit, D. Billington, P. Lattmann, C. Langley, Harjit Singh, S. Dunn (2006)
Novel anti-bacterials against MRSA: synthesis of focussed combinatorial libraries of tri-substituted 2(5H)-furanones.Current drug discovery technologies, 3 2
A. Karakurt, M. Ozalp, Ş. Işık, J. Stables, S. Dalkara (2010)
Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives.Bioorganic & medicinal chemistry, 18 8
Raquel Gutiérrez-Abad, Ona Illa, R. Ortuño (2010)
Synthesis of chiral cyclobutane containing C3-symmetric peptide dendrimers.Organic letters, 12 14
R. Cox, Dougal Ritson, Thomas Dane, J. Berge, J. Charmant, A. Kantacha (2005)
Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes.Chemical communications, 8
Sandip Murarka, A. Studer (2011)
Zinc triflate catalyzed aerobic cross-dehydrogenative coupling (CDC) of alkynes with nitrones: a new entry to isoxazoles.Organic letters, 13 10
Connor Martin, L. Overman, J. Rohde (2010)
Total synthesis of (+/-)- and (-)-actinophyllic acid.Journal of the American Chemical Society, 132 13
Y. Liao, R. Fathi, Zhen Yang (2003)
Aliphatic acetylenic homocoupling catalyzed by a novel combination of AgOTs-CuCl2-TMEDA and its application for the solid-phase synthesis of bis-benzo[b]furan-linked 1,3-diynes.Organic letters, 5 6
K. Brummond, Branko Mitasev (2004)
Allenes and transition metals: a diverging approach to heterocycles.Organic letters, 6 13
V. Lo, K. Kung, M. Wong, C. Che (2009)
Gold(III) (C^N) complex-catalyzed synthesis of propargylamines via a three-component coupling reaction of aldehydes, amines and alkynesJournal of Organometallic Chemistry, 694
Chitra Sundararajan, Travis Besanger, R. Labiris, Katharina Guenther, Thomas Strack, Robert Garafalo, T. Kawabata, D. Finco-Kent, J. Zubieta, J. Babich, J. Valliant (2010)
Synthesis and characterization of rhenium and technetium-99m labeled insulin.Journal of medicinal chemistry, 53 6
C. Kappe, E. Eycken (2010)
Click chemistry under non-classical reaction conditions.Chemical Society reviews, 39 4
G. Raner, Sean Cornelious, Kamalika Moulick, Ying-Qing Wang, Ashley Mortenson, N. Cech (2007)
Effects of herbal products and their constituents on human cytochrome P450(2E1) activity.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45 12
Edyta Gondela, K. Walczak (2010)
Synthesis and preliminary bioactivity assays of 3,4-dichloro-5-(omega-hydroxyalkylamino)-2(5H)-furanones.European journal of medicinal chemistry, 45 9
K. Prasad, V. Gandi (2010)
Formal total synthesis of (+)-didemniserinolipid BTetrahedron-asymmetry, 21
Meng-Xue Wei, Lei Feng, Xue-qiang Li, Xue-Zhang Zhou, Zhi-Hui Shao (2009)
Synthesis of new chiral 2,5-disubstituted 1,3,4-thiadiazoles possessing gamma-butenolide moiety and preliminary evaluation of in vitro anticancer activity.European journal of medicinal chemistry, 44 8
Using K2CO3 as a base and CH3CN as solvent, different kinds of N-[5-alkoxy-2(5H)-furanonyl] amino acids were reacted with propargyl bromide via substitution reaction at 40 °C to give 16 N-[5-alkoxy-2(5H)-furanonyl] amino acid propargyl esters with the yields of 44–85% (mostly over 74%). The structures of all newly synthesized compounds were elucidated and confirmed by FTIR, UV, 1H NMR, 13C NMR, MS, and elemental analysis. The rapid, efficient, and brief synthesis of the series propargyl esters with multiple bioactive units, will afford not only a basis for the activity test of potential drug molecules, but also an important synthetic strategy for 2(5H)-furanone derivatives with polyfunctional groups.
Research on Chemical Intermediates – Springer Journals
Published: Nov 16, 2011
Access the full text.
Sign up today, get DeepDyve free for 14 days.