4,8,9,10-tetraaryl-1,3-diazatricyclo[220.127.116.11]decan-6-ones are synthesized and reduced into its 4,8,9,10-tetraaryl-1,3-diazatricyclo[18.104.22.168]decan-6-ols (6a–m) with NaBH4 in methanol (2v), benzene (1v) mixture as the solvent system. These compounds are characterized using spectral data such as IR, 1H-NMR, and 13C-NMR data. These synthesized compounds are screened for their antimicrobial activity and were found to be effective anti-bacterials.
Research on Chemical Intermediates – Springer Journals
Published: Aug 14, 2014
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