Russian Journal of Applied Chemistry, 2011, Vol. 84, No. 5, pp. 847−853.
Pleiades Publishing, Ltd., 2011.
Original Russian Text © Yu.N. Bol’bukh, V.A. Tertykh, G.Yu. Yurkov, E.A. Ovchenkov, 2011, published in Zhurnal Prikladnoi Khimii, 2011, Vol. 84, No. 5,
AND POLYMERIC MATERIALS
Synthesis and Properties of Nanocomposites
Based on Magnetite and Biocompatible Polymers
Yu. N. Bol’bukh
, V. A. Tertykh
, G. Yu. Yurkov
, and E. A. Ovchenkov
Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine
Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Moscow, Russia
Lomonosov Moscow State University, Moscow, Russia
Received November 19, 2010
Abstract—Magnetosensitive composites were prepared on the basis of biocompatible polymers using Elmore
reaction. The structure of the composites and the morphology of the metal-containing component were examined.
The magnetic characteristics of the materials were studied.
Materials based on biocompatible or natural polymers
found wide use [1–3]. The major factor determining the
properties of nanocomposites, including those containing
magnetite, is the size of metal-containing particles. The
size of magnetite particles formed can be controlled by
varying the precursor, pyrolysis conditions, and method
for stabilization of the growing particles . The ﬁ nest
particles of size 5–7 nm are synthesized by the
Elmore reaction, whereas pyrolysis of precursors usually
yields particles approximately 50 nm in diameter .
In this study we examined certain properties of
composites based on magnetite and prepared by the
Elmore reaction using Mohr’s salt, with the particles
stabilized by 2-hydroxyethyl methacrylate monomer
in the course of its polymerization or by a natural
polymer, chitosan. Such materials can ﬁ nd use in sensor
engineering, as media for growth of biological objects,
in systems for drug delivery, and as sorbents.
For preparing iron-containing particles we used
O (chemically pure grade), Mohr’s salt
O (analytically pure grade),
and ammonium hydroxide (analytically pure grade)
(Khimreaktiv, Ukraine). As stabilizing matrix we used
chitosan, with glutaraldehyde (Fluka) as cross-linking
agent; also we used 2-hydroxyethyl methacrylate
(HEMA) (Fluka), with its polymerization initiated by
tetramethylethylenediamine (TMEDA) (Fluka).
In the synthesis of the composites based on chitosan,
the polymeric coating was formed in the step of particle
formation, with the subsequent cross-linking of chitosan
with glutaraldehyde. The weight ratio of the polymeric
and metal-containing phases was 1 : 1, and the Fe(II) :
Fe(III) molar ratio was 1 : 1. A weighed portion of the
mixture of the salts was dissolved in 3% acetic acid. The
mixture was heated to 60°С under a layer of toluene, and
OH was added. Then pH 7 of the dispersion
was adjusted, and a 1.5% solution of chitosan in 3%
acetic acid was
added. The mixture was stirred. After 20 min, the
mixture was alkalized to рН 10 with 15% ammonia
solution. In the ﬁ nal step, the mixture was acidiﬁ ed to
pH 7 with acetic acid, after which a 2.5% solution of
glutaraldehyde was added. After 30 min, the composite
obtained was repeatedly washed with water and ethanol
and then dried at 80°С.
The composite based on poly-HEMA was prepared
by introducing the monomer into the reaction medium
containing iron salts immediately after bringing the pH