Synthesis and in vitro microbiological evaluation of novel series of 8-hydroxy-2-(2-oxo-2H-chromen-3-yl)-5-phenyl-3H-chromeno [2,3-d]pyrimidin-4(5H)-one derivatives catalyzed by reusable silica-bonded N-propylpiperazine sulfamic acid

Synthesis and in vitro microbiological evaluation of novel series of... Silica-bonded propylpiperazine-N-sulfamic acid is employed as a recyclable catalyst for the synthesis of a series of 8-hydroxy-2-(2-oxo-2H-chromen-3-yl)-5-phenyl-3H-chromeno[2,3-d]pyrimidin-4(5H)-one derivatives by the condensation of 2-amino-3-cyano-7-hydroxy-4-phenyl-4Hchromene derivatives with coumarin-3-carboxylic acid. The heterogeneous catalyst was used for four runs. This method has the advantages of high yields, a cleaner reaction, simple methodology, short reaction times, and easy work-up. All the compounds were evaluated for their in vitro antimicrobial activity against different bacterial and fungal strains. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Synthesis and in vitro microbiological evaluation of novel series of 8-hydroxy-2-(2-oxo-2H-chromen-3-yl)-5-phenyl-3H-chromeno [2,3-d]pyrimidin-4(5H)-one derivatives catalyzed by reusable silica-bonded N-propylpiperazine sulfamic acid

Loading next page...
 
/lp/springer_journal/synthesis-and-in-vitro-microbiological-evaluation-of-novel-series-of-8-tZXsdqgHHi
Publisher
Springer Netherlands
Copyright
Copyright © 2013 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-013-1419-2
Publisher site
See Article on Publisher Site

Abstract

Silica-bonded propylpiperazine-N-sulfamic acid is employed as a recyclable catalyst for the synthesis of a series of 8-hydroxy-2-(2-oxo-2H-chromen-3-yl)-5-phenyl-3H-chromeno[2,3-d]pyrimidin-4(5H)-one derivatives by the condensation of 2-amino-3-cyano-7-hydroxy-4-phenyl-4Hchromene derivatives with coumarin-3-carboxylic acid. The heterogeneous catalyst was used for four runs. This method has the advantages of high yields, a cleaner reaction, simple methodology, short reaction times, and easy work-up. All the compounds were evaluated for their in vitro antimicrobial activity against different bacterial and fungal strains.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Oct 5, 2013

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off