Synthesis and evaluation of biological activities
of new sulfonamide and carbamate derivatives
of 1H-pyrrolo[2,3-b]pyridine (7-azaindole)
S. K. Thaslim Basha
S. Muni Chandra Reddy
C. Naga Raju
Received: 23 October 2015 / Accepted: 12 April 2016 / Published online: 25 April 2016
Ó Springer Science+Business Media Dordrecht 2016
Synthesis of a new series of sulfonamide and carbamate derivatives of
7-azaindole and evaluation of their anti-TMV and anti-oxidant activities are reported.
Their chemical structures were characterized by IR,
C NMR, mass and HRMS
spectral analysis. The biological assay revealed that the compounds 4-nitrophenyl 1H-
pyrrolo[2,3-b]pyridine-1-carboxylate (9g) and 4-nitrobenzyl 1H-pyrrolo[2,3-b]pyridine-
1-carboxylate (9h) exhibited high inhibition against tobacco mosaic virus and abstraction
of free radicals.
Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2547-2)
contains supplementary material, which is available to authorized users.
& C. Naga Raju
Department of Chemistry, S. V. University, Tirupati, Andhra Pradesh 517 502, India
Department of Chemistry, Vikrama Simhapuri University, Nellore, Andhra Pradesh 524 003,
Nanotechnology Laboratory, Institute of Frontier Technology, Regional Agricultural Research
Station (RARS), Tirupati, Andhra Pradesh 517 502, India
Res Chem Intermed (2016) 42:7471–7486