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Synthesis and antimicrobial properties of 3-(β-hydroxyethyl)-1,3-oxazolidins

Synthesis and antimicrobial properties of 3-(β-hydroxyethyl)-1,3-oxazolidins The possibility of synthesis of 3-(β-hydroxyethyl)-1,3-oxazolidin and its substituted derivatives at position 2 by the condensation-heterocyclization of diethanolamine with certain aldehydes and ketones was examined. The structure of the compounds was identifi ed by NMR spectroscopy. We investigated antimicrobial properties of the synthesized compounds against microorganisms that affect the lube oil M-11 and found a dependence of the antimicrobial properties on the nature of the substituent at position 2 of oxazolidin heterocycle. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Applied Chemistry Springer Journals

Synthesis and antimicrobial properties of 3-(β-hydroxyethyl)-1,3-oxazolidins

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References (2)

Publisher
Springer Journals
Copyright
Copyright © 2012 by Pleiades Publishing, Ltd.
Subject
Chemistry; Industrial Chemistry/Chemical Engineering; Chemistry/Food Science, general
ISSN
1070-4272
eISSN
1608-3296
DOI
10.1134/S1070427212010168
Publisher site
See Article on Publisher Site

Abstract

The possibility of synthesis of 3-(β-hydroxyethyl)-1,3-oxazolidin and its substituted derivatives at position 2 by the condensation-heterocyclization of diethanolamine with certain aldehydes and ketones was examined. The structure of the compounds was identifi ed by NMR spectroscopy. We investigated antimicrobial properties of the synthesized compounds against microorganisms that affect the lube oil M-11 and found a dependence of the antimicrobial properties on the nature of the substituent at position 2 of oxazolidin heterocycle.

Journal

Russian Journal of Applied ChemistrySpringer Journals

Published: Feb 17, 2012

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