Four mancozeb derivatives containing 1,3,4-thiadiazole, 5a–5d, were successfully synthesized, then characterized by IR, 1H NMR, and 13C NMR spectroscopy and elemental analysis. Their antimicrobial activity against paddy fusarium, Botrytis cinerea, cucumber fusarium, tomato gibberella, and grape white rot was tested in vitro by use of the filter paper disk-diffusion technique. Compounds 5a–5d had moderate to excellent antimicrobial activity in comparison with mancozeb, 6. Among these compounds, 5a had the best inhibitory activity.
Research on Chemical Intermediates – Springer Journals
Published: Jun 29, 2013
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