Synthesis and antimicrobial activity of new urea and thiourea derivatives of (2′-(1H-tetrazol-5-yl)biphenyl-4-yl)methanamine

Synthesis and antimicrobial activity of new urea and thiourea derivatives of... Antibacterial N N N N N N NH activity HN N HN N R-NCX X=S,O Antifunagl activity Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2823- 1) contains supplementary material, which is available to authorized users. & Chamarthi Naga Raju Department of Chemistry, Sri Venkateswara University, Tirupati, A.P. 517502, India 123 3252 P. Vedavathi et al. Keywords Isocyanates  Isothiocyanates  (2 -(1H-Tetrazol-5-yl)biphenyl-4- yl)methanamine  Antibacterial activity  Antifungal activity Introduction Heterocyclic compounds are privileged structures in drug discovery, representing one of the major research areas in medicinal chemistry. The class of heterocycle compounds is especially relevant to life processes due to their enzymatic functions and hereditary information transfer, also finding applications in medicine, agricul- ture, and industry as well as different areas of chemistry. Heterocyclic compounds are often used in nanochemistry, molecular devices and sensors, combinatorial and supramolecular chemistry, as well as catalysis. Furthermore, important types of ionic liquid (IL) composed of heterocyclic compounds are useful in pharmaceutical industry as green solvents and catalysts. More specifically, nitrogen heterocycles are a class of naturally occurring compounds essential to life, since their structural units are present in many natural products such as vitamins, hormones, antibiotics, alkaloids, as well Research on Chemical Intermediates Springer Journals

Synthesis and antimicrobial activity of new urea and thiourea derivatives of (2′-(1H-tetrazol-5-yl)biphenyl-4-yl)methanamine

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Springer Netherlands
Copyright © 2016 by Springer Science+Business Media Dordrecht
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
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