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A. Amr, A. Mohamed, A. Ibrahim (2003)
Synthesis of Some New Chiral Tricyclic and Macrocyclic Pyridine Derivatives as Antimicrobial AgentsZeitschrift für Naturforschung B, 58
J. Chakrabarti, L. Horsman, T. Hotten, I. Pullar, D. Tupper, F. Wright (1980)
4-Piperazinyl-10H-thieno[2,3-b][1,5]benzodiazepines as potential neuroleptics.Journal of medicinal chemistry, 23 8
C. Kurumurthy, P. Rao, B. swamy, G. kumar, P. Rao, B. Narsaiah, L. Velatooru, R. Pamanji, J. Rao (2011)
Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity.European journal of medicinal chemistry, 46 8
D. Lorrain, H. Schaffhauser, U. Campbell, C. Baccei, L. Correa, B. Rowe, D. Rodriguez, Jeffery Anderson, M. Varney, A. Pinkerton, J. Vernier, L. Bristow (2003)
Group II mGlu Receptor Activation Suppresses Norepinephrine Release in the Ventral Hippocampus and Locomotor Responses to Acute Ketamine ChallengeNeuropsychopharmacology, 28
Jacorien Coetzee, S. Cronje, L. Dobrzańska, H. Raubenheimer, G. Jooné, M. Nell, H. Hoppe (2011)
Novel N-heterocyclic ylideneamine gold(I) complexes: synthesis, characterisation and screening for antitumour and antimalarial activity.Dalton transactions, 40 7
F. Anderson, G. Grail, F. Leonard, L. Tenenbaum, J. Hart, F. Barkley (1956)
The antituberculous activity of some isonicotinic acid hydrazide congeners and derivatives.Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 45 5
S. Mohamed, M. Youssef, A. Amr, E. Kotb (2008)
Antimicrobial Activities of some Synthesized Pyridines, Oxazines and Thiazoles from 3-Aryl-1 -(2-naphthyl)prop-2-en-1 -onesScientia Pharmaceutica, 76
A. Tostmann, M. Boeree, R. Aarnoutse, W. Lange, A. Ven, R. Dekhuijzen (2008)
Antituberculosis drug‐induced hepatotoxicity: Concise up‐to‐date reviewJournal of Gastroenterology and Hepatology, 23
M. Al-Omar, A. Amr (2010)
Synthesis of Some New Pyridine-2,6-carboxamide-derived Schiff Bases as Potential Antimicrobial AgentsMolecules, 15
H. Fahmy, W. El-Eraky (2001)
Synthesis and evaluation of the analgesic and antiinflammatory activities ofO-Substituted salicylamidesArchives of Pharmacal Research, 24
Jiangtao Wang, Hedong Wang (2011)
Preparation of soluble p-aminobenzoyl chitosan ester by Schiff's base and antibacterial activity of the derivatives.International journal of biological macromolecules, 48 3
A. Amr, A. Mohamed, S. Mohamed, N. Abdel-Hafez, A. Hammam (2006)
Anticancer activities of some newly synthesized pyridine, pyrane, and pyrimidine derivatives.Bioorganic & medicinal chemistry, 14 16
T. Sarich, T. Zhou, S. Adams, A. Bain, R. Wall, J. Wright (1995)
A model of isoniazid-induced hepatotoxicity in rabbits.Journal of pharmacological and toxicological methods, 34 2
A. Tjølsen, Jan Rosland, O. Berge, K. Hole (1991)
The increasing-temperature hot-plate test: an improved test of nociception in mice and rats.Journal of pharmacological methods, 25 3
E. Declercq (1986)
Potential of bromovinyldeoxyuridine in anticancer chemotherapy.Anticancer Research, 6
M. Al-Omar, A. Amr, R. Al-Salahi (2010)
Anti‐inflammatory, Analgesic, Anticonvulsant and Antiparkinsonian Activities of Some Pyridine Derivatives Using 2,6‐Disubstituted Isonicotinic Acid HydrazidesArchiv der Pharmazie, 343
R. Al-Salahi, M. Al-Omar, A. Amr (2010)
Synthesis of Chiral Macrocyclic or Linear Pyridine Carboxamides from Pyridine-2,6-dicarbonyl Dichloride as Antimicrobial AgentsMolecules, 15
V. Ram, Vidyohama Dube, A. Vlietinck (1987)
Triazolotriazines as potential chemotherapeutic agents. VIJournal of Heterocyclic Chemistry, 24
A. Amr, O. El-Salam, A. Attia, I. Stibor (1999)
Synthesis of New Potential Bis-Intercalators Based on Chiral Pyridine-2,6-dicarboxamidesCollection of Czechoslovak Chemical Communications, 64
A series of novel 2-(2-(substituted benzylidene)hydrazinyl)-N′-(substituted benzylidene)-6-chloropyridine-4-carbohydrazide (5a–e), 2-(2-cycloalkylidenehydrazinyl)-6-chloro-N’-cyclo-alkylidenepyridine-4-carbohydrazide (6a,b), 2-(2-(1-(4-substituted phenyl)ethylidene)hydrazinyl)-6-chloro-N′-(1-(4-substituted phenyl)ethylidene)pyridine-4-carbohydrazide (7a,b) and 2-(2-(1-(pyridinyl)ethylidene)hydrazinyl)-6-chloro-N′-(1-(pyridinyl) ethylidene)pyridine-4-carbo-hydrazide (8a–c) derivatives have been synthesized by treating treating 2-chloro-6-hydrazinoisonicotinic acid hydrazide 4 with selected active reagents. Their structures were confirmed by spectral and analytical data. The synthesized compounds were investigated for antimicrobial activities. The antimicrobial screening showed that many of these obtained compounds have good activities comparable to Streptomycin and Fusidic acid as reference drugs.
Research on Chemical Intermediates – Springer Journals
Published: Jan 22, 2013
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