Synchronous colorectal liver metastases: focus on the elderly

Synchronous colorectal liver metastases: focus on the elderly Langenbecks Arch Surg (2017) 402:1223–1232 DOI 10.1007/s00423-017-1611-8 ORIGINAL ARTICLE An Effectiveness Study from Routine Care 1 1 1 2 Markus Albertsmeier & Andrea Engel & Markus O. Guba & Sebastian Stintzing & 1 3 3 1 Tobias S. Schiergens & Gabriele Schubert-Fritschle & Dieter Hölzel & Jens Werner & 1 3 Martin K. Angele & Jutta Engel Received: 8 January 2017 /Accepted: 20 July 2017 /Published online: 12 August 2017 Springer-Verlag GmbH Germany 2017 Abstract lower compared to younger patients (OS 34.3 vs. 43.5%, Purpose The goal of this study was to analyze the use and the P = 0.0114). In a Cox regression model, complete surgical effectiveness of both surgery and different chemotherapies in removal of liver metastases was the most effective treatment patients with synchronous colorectal liver metastases (CLMs) (HR 0.313, P < 0.001) followed by chemotherapy (irinotecan/ ≥70 years compared to younger patients. platin-based: HR 0.371, 5-FU only: HR 0.673, P <0.001). Methods Survival was analyzed in 456 patients (24.3% Having >5 liver metastases, the presence of extrahepatic metas- ≥70 years) treated for CLM in a single center using Kaplan- tases, high grading, and a nodal positive primary but not age Meier estimation of overall survival http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Langenbeck's Archives of Surgery Springer Journals
Loading next page...
 
/lp/springer_journal/synchronous-colorectal-liver-metastases-focus-on-the-elderly-OdonFegPbE
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; General Surgery; Abdominal Surgery; Cardiac Surgery; Thoracic Surgery; Traumatic Surgery; Vascular Surgery
ISSN
1435-2443
eISSN
1435-2451
D.O.I.
10.1007/s00423-017-1611-8
Publisher site
See Article on Publisher Site

Abstract

Langenbecks Arch Surg (2017) 402:1223–1232 DOI 10.1007/s00423-017-1611-8 ORIGINAL ARTICLE An Effectiveness Study from Routine Care 1 1 1 2 Markus Albertsmeier & Andrea Engel & Markus O. Guba & Sebastian Stintzing & 1 3 3 1 Tobias S. Schiergens & Gabriele Schubert-Fritschle & Dieter Hölzel & Jens Werner & 1 3 Martin K. Angele & Jutta Engel Received: 8 January 2017 /Accepted: 20 July 2017 /Published online: 12 August 2017 Springer-Verlag GmbH Germany 2017 Abstract lower compared to younger patients (OS 34.3 vs. 43.5%, Purpose The goal of this study was to analyze the use and the P = 0.0114). In a Cox regression model, complete surgical effectiveness of both surgery and different chemotherapies in removal of liver metastases was the most effective treatment patients with synchronous colorectal liver metastases (CLMs) (HR 0.313, P < 0.001) followed by chemotherapy (irinotecan/ ≥70 years compared to younger patients. platin-based: HR 0.371, 5-FU only: HR 0.673, P <0.001). Methods Survival was analyzed in 456 patients (24.3% Having >5 liver metastases, the presence of extrahepatic metas- ≥70 years) treated for CLM in a single center using Kaplan- tases, high grading, and a nodal positive primary but not age Meier estimation of overall survival

Journal

Langenbeck's Archives of SurgerySpringer Journals

Published: Aug 12, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off