Breast Cancer Res Treat (2017) 165:311–320 DOI 10.1007/s10549-017-4331-4 CLINICAL TRIAL Survival improvement in hormone-responsive young breast cancer patients with endocrine therapy 2 3 1 1 1 • • • • • Tae In Yoon Ui-Kang Hwang Eui Tae Kim SaeByul Lee Guiyun Sohn 1 1 1 4 • • • • Beom Seok Ko Jong Won Lee Byung Ho Son Seonok Kim 1 1 Sei Hyun Ahn Hee Jeong Kim Received: 30 May 2017 / Accepted: 2 June 2017 / Published online: 10 June 2017 Springer Science+Business Media, LLC 2017 Abstract therapy. The younger patients with hormone receptor Purpose We investigated the oncologic outcomes by (HR)-positive tumors showed signiﬁcantly poorer disease- intrinsic subtype and age in young breast cancer patients free survival (DFS), loco-regional recurrence-free survival, and whether survival differences were related to treatment distant metastasis-free survival, and breast cancer-speciﬁc changes over time. survival outcomes than older patients. Younger patients Methods A retrospective analysis was performed on 9633 with HR-positive and human epidermal growth factor invasive breast cancer patients treated at Asan Medical receptor 2 (HER2)-negative tumor subtypes had a signiﬁ- Center from January 1989 to December 2008. We also cantly improved DFS over time (p = 0.032). Within
Breast Cancer Research and Treatment – Springer Journals
Published: Jun 10, 2017
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