Access the full text.
Sign up today, get DeepDyve free for 14 days.
Junzhong Lin, J. Peng, A. Qdaisat, Li-ren Li, Gong Chen, Zhen-hai Lu, Xiaojun Wu, Yuan-hong Gao, Z. Zeng, P. Ding, Z. Pan (2016)
Severe weight loss during preoperative chemoradiotherapy compromises survival outcome for patients with locally advanced rectal cancerJournal of Cancer Research and Clinical Oncology, 142
R. Sauer, H. Becker, W. Hohenberger, C. Rödel, C. Wittekind, R. Fietkau, P. Martus, J. Tschmelitsch, E. Hager, C. Hess, J. Karstens, T. Liersch, H. Schmidberger, R. Raab (2004)
Preoperative versus postoperative chemoradiotherapy for rectal cancer.The New England journal of medicine, 351 17
S. Merkel, V. Schellerer, K. Weber, J. Göhl, W. Hohenberger (2012)
Assessment of advances of outcome quality in colon carcinoma at a single centerColorectal cancer, 1
(2009)
TNM classification of malignant tumours 7th edn
Y. Chua, D. Sargent, D. Cunningham (2005)
Definition of disease-free survival: this is my truth-show me yours.Annals of oncology : official journal of the European Society for Medical Oncology, 16 11
M Greenwood (1926)
The errors of sampling of the survivorship table reports on public health and medical subjects
M. Chand, M. Chand, M. Chand, A. Bhangu, A. Bhangu, A. Bhangu, A. Wotherspoon, A. Wotherspoon, G. Stamp, G. Stamp, R. Swift, I. Chau, P. Tekkis, P. Tekkis, G. Brown (2014)
EMVI-positive stage II rectal cancer has similar clinical outcomes as stage III disease following pre-operative chemoradiotherapy.Annals of oncology : official journal of the European Society for Medical Oncology, 25 4
C. Wittekind, M. Gospodarowicz, L. Sobin (2009)
Comprar TNM Classification of Malignant Tumours, 7th Edition | C. Wittekind | 9781444332414 | Wiley
Dexin Jiao, Rui Zhang, Zhiqiang Gong, Fang Liu, Yue Chen, Qinrui Yu, Liping Sun, H. Duan, Shendong Zhu, Fei Liu, Jian Wang, Jianhui Jia (2015)
Fluorouracil-based preoperative chemoradiotherapy with or without oxaliplatin for stage II/III rectal cancer: a 3-year follow-up study.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 27 6
Soo-Young Lee, Jeong Jo, Hun Kim, Chang-Hyun Kim, Y. Kim, Hyeong-Rok Kim (2015)
Prognostic factors for low rectal cancer patients undergoing intersphincteric resection after neoadjuvant chemoradiationJournal of Surgical Oncology, 111
D. Sargent, H. Wieand, D. Haller, R. Gray, J. Benedetti, M. Buyse, R. Labianca, J. Seitz, C. O'Callaghan, G. Francini, A. Grothey, M. O’connell, P. Catalano, C. Blanke, D. Kerr, E. Green, N. Wolmark, T. André, R. Goldberg, A. Gramont (2004)
Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 34
K. Bujko, M. Nowacki, A. Nasierowska-Guttmejer, W. Michalski, M. Bębenek, M. Pudełko, M. Kryj, J. Olędzki, J. Szmeja, J. Słuszniak, K. Serkies, J. Kładny, M. Pamucka, P. Kukołowicz (2004)
Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 72 1
R. Glynne-Jones, N. Counsell, P. Quirke, N. Mortensen, A. Maraveyas, H. Meadows, J. Ledermann, D. Sebag‐Montefiore (2014)
Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control.Annals of oncology : official journal of the European Society for Medical Oncology, 25 7
D. Sargent, S. Patiyil, G. Yothers, D. Haller, R. Gray, J. Benedetti, M. Buyse, R. Labianca, J. Seitz, C. O'Callaghan, G. Francini, A. Grothey, M. O’connell, P. Catalano, D. Kerr, E. Green, H. Wieand, R. Goldberg, A. Gramont (2007)
End points for colon cancer adjuvant trials: observations and recommendations based on individual patient data from 20,898 patients enrolled onto 18 randomized trials from the ACCENT Group.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 25 29
R. Sauer, T. Liersch, S. Merkel, R. Fietkau, W. Hohenberger, C. Hess, H. Becker, H. Raab, Marie-Therese Villanueva, H. Witzigmann, C. Wittekind, T. Beissbarth, C. Rödel (2012)
Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30 16
R. Glynne-Jones, S. Mawdsley, T. Pearce, Marc Buyse (2006)
Alternative clinical end points in rectal cancer--are we getting closer?Annals of oncology : official journal of the European Society for Medical Oncology, 17 8
M. Roh, L. Colangelo, M. O’connell, G. Yothers, M. Deutsch, C. Allegra, M. Kahlenberg, Luis Baez-Diaz, Carol Ursiny, N. Petrelli, N. Wolmark (2009)
Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27 31
R. Hofheinz, F. Wenz, S. Post, A. Matzdorff, S. Lächelt, J. Hartmann, L. Müller, H. Link, M. Moehler, E. Kettner, E. Fritz, U. Hieber, H. Lindemann, M. Grunewald, S. Kremers, C. Constantin, M. Hipp, G. Hartung, D. Gencer, P. Kienle, I. Burkholder, A. Hochhaus (2012)
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.The Lancet. Oncology, 13 6
I. Park, C. Yu, Seok-Byung Lim, Y. Yoon, C. Kim, Tae Kim, Jong Kim, J. Kim (2014)
Prognostic Implications of the Number of Retrieved Lymph Nodes of Patients with Rectal Cancer Treated with Preoperative ChemoradiotherapyJournal of Gastrointestinal Surgery, 18
J. Gérard, T. Conroy, F. Bonnetain, O. Bouché, O. Chapet, M. Closon-Dejardin, M. Untereiner, B. Leduc, E. François, J. Maurel, J. Seitz, B. Buecher, R. Mackiewicz, M. Ducreux, L. Bedenne (2006)
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 28
J. Bosset, Laurence Collette, Gilles Calais, Laurent Mineur, Philippe Maingon, Ljiljana Radosevic-Jelic, Alain Daban, É. Bardet, Alexander Beny, Jean-Claude Ollier (2006)
Chemotherapy with preoperative radiotherapy in rectal cancer.The New England journal of medicine, 355 11
S. Merkel, Ulrich Mansmann, Werner Hohenberger, P. Hermanek (2011)
Time to locoregional recurrence after curative resection of rectal carcinoma is prolonged after neoadjuvant treatment: a systematic review and meta‐analysisColorectal Disease, 13
Karla Geiss, M. Meyer, M. Radespiel-Tröger, O. Gefeller (2009)
SURVSOFT - Software for nonparametric survival analysisComputer methods and programs in biomedicine, 96 1
C. Rödel, T. Liersch, H. Becker, R. Fietkau, W. Hohenberger, T. Hothorn, U. Graeven, D. Arnold, M. Lang-Welzenbach, H. Raab, H. Sülberg, C. Wittekind, Sergej Potapov, L. Staib, C. Hess, K. Weigang-Köhler, G. Grabenbauer, H. Hoffmanns, F. Lindemann, A. Schlenska-Lange, G. Folprecht, R. Sauer (2012)
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.The Lancet. Oncology, 13 7
Y. Sun, Pan Chi, Hui-ming Lin, Xingrong Lu, Ying Huang, Zongbin Xu, Shenghui Huang, Xiaojie Wang (2017)
Inferior mesenteric artery lymph node metastasis in rectal cancer treated with neoadjuvant chemoradiotherapy: Incidence, prediction and prognostic impact.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 43 1
M. Chand, R. Swift, P. Tekkis, I. Chau, G. Brown, G. Brown (2013)
Extramural venous invasion is a potential imaging predictive biomarker of neoadjuvant treatment in rectal cancerBritish Journal of Cancer, 110
O. Dworak, L. Keilholz, A. Hoffmann (1997)
Pathological features of rectal cancer after preoperative radiochemotherapyInternational Journal of Colorectal Disease, 12
M. Braendengen, K. Tveit, A. Berglund, Elke Birkemeyer, G. Frykholm, L. Påhlman, J. Wiig, P. Byström, K. Bujko, B. Glimelius (2008)
Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26 22
S. Merkel, T. Meyer, J. Göhl, W. Hohenberger (2002)
Late locoregional recurrence in rectal carcinoma.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 28 7
Int J Colorectal Dis (2017) 32:1295–1301 DOI 10.1007/s00384-017-2861-1 ORIGINAL ARTICLE Survival analysis in rectal carcinoma after neoadjuvant chemoradiation: various methods with different results 1,2 1 1 3 4 Susanne Merkel & Klaus Weber & Jonas Göhl & Abbas Agaimy & Rainer Fietkau & 1 1 1 Werner Hohenberger & Robert Grützmann & Paul Hermanek Accepted: 7 July 2017 /Published online: 20 July 2017 Springer-Verlag GmbH Germany 2017 Abstract y0 and highest in UICC stage yIV. The 3-year DFS-rate was Purpose Survival is an important indicator of outcome quality always lower (worse) than the 5-year OS rate and higher in rectal carcinoma. The 5-year survival rate is the typical (better) than the 7-year OS rate, with the exception of stage outcome measurement. In patients with neoadjuvant chemo- yIV. radiation followed by curative surgery, 7 years of follow-up is Conclusions Comparisons of survival are only meaningful if recommended. Different methods of survival analysis lead to the same methods are applied. The 3-year rate of DFS was different results. Here, we compared four different methods. always worse than the rate of 5-year OS. Therefore, the 3-year Methods The data of 439 patients with rectal carcinoma treat- rate of DFS appears to be
International Journal of Colorectal Disease – Springer Journals
Published: Jul 20, 2017
Access the full text.
Sign up today, get DeepDyve free for 14 days.