Int J Colorectal Dis (2017) 32:1295–1301 DOI 10.1007/s00384-017-2861-1 ORIGINAL ARTICLE Survival analysis in rectal carcinoma after neoadjuvant chemoradiation: various methods with different results 1,2 1 1 3 4 Susanne Merkel & Klaus Weber & Jonas Göhl & Abbas Agaimy & Rainer Fietkau & 1 1 1 Werner Hohenberger & Robert Grützmann & Paul Hermanek Accepted: 7 July 2017 /Published online: 20 July 2017 Springer-Verlag GmbH Germany 2017 Abstract y0 and highest in UICC stage yIV. The 3-year DFS-rate was Purpose Survival is an important indicator of outcome quality always lower (worse) than the 5-year OS rate and higher in rectal carcinoma. The 5-year survival rate is the typical (better) than the 7-year OS rate, with the exception of stage outcome measurement. In patients with neoadjuvant chemo- yIV. radiation followed by curative surgery, 7 years of follow-up is Conclusions Comparisons of survival are only meaningful if recommended. Different methods of survival analysis lead to the same methods are applied. The 3-year rate of DFS was different results. Here, we compared four different methods. always worse than the rate of 5-year OS. Therefore, the 3-year Methods The data of 439 patients with rectal carcinoma treat- rate of DFS appears to be
International Journal of Colorectal Disease – Springer Journals
Published: Jul 20, 2017
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