Surgical treatment of Fournier’s gangrene: use of cultured allogeneic keratinocytes

Surgical treatment of Fournier’s gangrene: use of cultured allogeneic keratinocytes We discuss the value of the use of skin culturing as an addition to the classic treatment of Fournier’s gangrene. A 32-year-old morbidly obese man was admitted with signs of a severe septic shock syndrome due to Fournier’s gangrene. He recovered completely after an aggressive surgical débridement, combined with the use of broad spectrum antibiotics and invasive ventilator support for respiratory failure. The surgical reconstruction of the extensive skin defects following removal of the infected skin and soft tissues was successfully achieved with a combined application of meshed autologous skin grafts and the use of cultured allogeneic keratinocytes. Early cover of large skin defects is a major therapeutic goal, regardless of the nature of the primary etiology. The combined use of meshed autologous skin grafts and cultured keratinocytes represents one of the newer techniques. The contribution of this technique on the quality of healing and coverage of extensive skin loss zones is being investigated, since it seems to be a valuable option in reconstructing some of the sequelae of Fournier’s gangrene. European Journal of Plastic Surgery Springer Journals

Surgical treatment of Fournier’s gangrene: use of cultured allogeneic keratinocytes

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Copyright © 2000 by Springer-Verlag Berlin Heidelberg
Medicine & Public Health; Plastic Surgery
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