Surgical treatment of Fournier’s gangrene: use of cultured allogeneic keratinocytes

Surgical treatment of Fournier’s gangrene: use of cultured allogeneic keratinocytes We discuss the value of the use of skin culturing as an addition to the classic treatment of Fournier’s gangrene. A 32-year-old morbidly obese man was admitted with signs of a severe septic shock syndrome due to Fournier’s gangrene. He recovered completely after an aggressive surgical débridement, combined with the use of broad spectrum antibiotics and invasive ventilator support for respiratory failure. The surgical reconstruction of the extensive skin defects following removal of the infected skin and soft tissues was successfully achieved with a combined application of meshed autologous skin grafts and the use of cultured allogeneic keratinocytes. Early cover of large skin defects is a major therapeutic goal, regardless of the nature of the primary etiology. The combined use of meshed autologous skin grafts and cultured keratinocytes represents one of the newer techniques. The contribution of this technique on the quality of healing and coverage of extensive skin loss zones is being investigated, since it seems to be a valuable option in reconstructing some of the sequelae of Fournier’s gangrene. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

Surgical treatment of Fournier’s gangrene: use of cultured allogeneic keratinocytes

Loading next page...
 
/lp/springer_journal/surgical-treatment-of-fournier-s-gangrene-use-of-cultured-allogeneic-TRXbwJH6cI
Publisher
Springer Journals
Copyright
Copyright © 2000 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Plastic Surgery
ISSN
0930-343X
eISSN
1435-0130
D.O.I.
10.1007/s002380000188
Publisher site
See Article on Publisher Site

Abstract

We discuss the value of the use of skin culturing as an addition to the classic treatment of Fournier’s gangrene. A 32-year-old morbidly obese man was admitted with signs of a severe septic shock syndrome due to Fournier’s gangrene. He recovered completely after an aggressive surgical débridement, combined with the use of broad spectrum antibiotics and invasive ventilator support for respiratory failure. The surgical reconstruction of the extensive skin defects following removal of the infected skin and soft tissues was successfully achieved with a combined application of meshed autologous skin grafts and the use of cultured allogeneic keratinocytes. Early cover of large skin defects is a major therapeutic goal, regardless of the nature of the primary etiology. The combined use of meshed autologous skin grafts and cultured keratinocytes represents one of the newer techniques. The contribution of this technique on the quality of healing and coverage of extensive skin loss zones is being investigated, since it seems to be a valuable option in reconstructing some of the sequelae of Fournier’s gangrene.

Journal

European Journal of Plastic SurgerySpringer Journals

Published: Oct 16, 2000

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off