Eur J Plast Surg (2012) 35:625–627 DOI 10.1007/s00238-011-0568-z CASE REPORT Colin Patrick White & Stuart Martin & Arianna Dal Cin Received: 2 February 2011 /Accepted: 2 March 2011 /Published online: 13 May 2011 Springer-Verlag 2011 Introduction Neurofibromas are very common and characterized by a noticeable proliferation of fibroblasts, of neural mast cells and Neurofibromatosis type 1 (NF1) is an autosomal dominant Schwann cells. These benign growths develop along the condition with well-recognized clinical signs . Skin cutaneous and mucosal nerves of the body as well as visceral lesions, benign tumors of peripheral nerves, and sometimes nerves of the internal organs. Related osseous alterations such tumors of the central nervous system characterize neurofi- as kyphoscoliosis, pseudarthrosis, and erosive lesions of the bromatosis clinically . These tumors were first described long bones are frequent. Eye conditions such as hamartomas by Smith in 1849 and later by Von Recklinghausen in 1882 of the iris and Lisch nodules (a pigmented hamartomatous . Hence, NF is also known as Von Recklinghausen’s nevus affecting the iris ) are less common [7, 8]. disease. It has an incidence of approximately 1 in 3,000 live Surgery is usually performed for neurofibromas that are births . painful, infected,
European Journal of Plastic Surgery – Springer Journals
Published: Aug 1, 2012
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