Surgical management of Darier's disease affecting the feet

Surgical management of Darier's disease affecting the feet Darier's disease is an autosomal dominant condition of variable severity affecting the skin, nails and mucosa. A 37-year-old man with Darier's disease on the soles of both feet was medically managed with oral retinoids, but areas of disease continued to fissure and cause excruciating pain. Surgical management with excision of diseased skin and resurfacing with split skin grafting was successful. There has been no disease recurrence at 6-month follow-up. This is the first reported case of excision and skin grafting for Darier's disease in the foot, a notoriously difficult area to operate on successfully. It also adds further evidence to the beneficial outcomes of surgical management in Darier's disease. Level of Evidence: Level V, therapeutic study. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

Surgical management of Darier's disease affecting the feet

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Publisher
Springer Journals
Copyright
Copyright © 2014 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Plastic Surgery
ISSN
0930-343X
eISSN
1435-0130
D.O.I.
10.1007/s00238-013-0876-6
Publisher site
See Article on Publisher Site

Abstract

Darier's disease is an autosomal dominant condition of variable severity affecting the skin, nails and mucosa. A 37-year-old man with Darier's disease on the soles of both feet was medically managed with oral retinoids, but areas of disease continued to fissure and cause excruciating pain. Surgical management with excision of diseased skin and resurfacing with split skin grafting was successful. There has been no disease recurrence at 6-month follow-up. This is the first reported case of excision and skin grafting for Darier's disease in the foot, a notoriously difficult area to operate on successfully. It also adds further evidence to the beneficial outcomes of surgical management in Darier's disease. Level of Evidence: Level V, therapeutic study.

Journal

European Journal of Plastic SurgerySpringer Journals

Published: Jan 1, 2014

References

  • The phenotype of Darier's disease: penetrance and expressivity in adults and children
    Munro, CS

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