A series 1-amidoalkyl-2-naphthols were synthesized by one-pot three-component condensation reaction of β-naphthol with various aromatic aldehydes and amides under thermal (hot plate and oil bath) and microwave techniques. and the effect of various organoacids used as catalyst was studied. Among the various acids screened, p-aminobezene sulphonic acid (sulfanilic acid) came out to be a versatile catalyst and the corresponding products were obtained in good to excellent yield (84–94 %) under solvent-free condition.
Research on Chemical Intermediates – Springer Journals
Published: Jan 4, 2014
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