Sulfamic acid-catalyzed multicomponent synthesis of 7-phenyl-7,12 dihydrobenzo(h)pyrido[2,3-b]naphthydrin-6(5H)-one derivatives: a green avenue

Sulfamic acid-catalyzed multicomponent synthesis of 7-phenyl-7,12... Keywords Atom economy  Multicomponent reactions  Sulfamic acid  2-Amino pyridine  Naphthydrin derivatives Introduction Multistep synthesis of complex organic molecules does not meet the criteria of green chemistry because of several drawbacks such as the generation of waste, longer reaction time, low yield, tedious work-up procedure, etc. To overcome this issue, the scientific community has recently turned their attention towards an enviro- economic synthesis. Multicomponent reactions (MCRs) are ideal tools to overcome these drawbacks due to their remarkable advantages like high convergence, operational simplicity, facile automation, efficient work-up procedure, minimum waste generation, and enhancement atom economics rendering the protocol green [1, 2]. MCRs strategy has been realized to be a powerful means of developing drug- like heterocyclic compounds with high levels of diversity and molecular complex- ity, thereby facilitating optimization in organic synthesis [3, 4]. Therefore, the design of new MCRs with green procedures has attracted great attention, particularly in the areas of organic synthesis [5–9]. The naphthydrin skeleton, being a crucial pharmacophore present in various synthetic compounds as well as in natural products, has attracted considerable attention [10]. Neozeylanicine from the wood of Neonaucleazeylanica [11, 12], naphthyridiyl methyl ketone from Valeriana officinalis [13, 14], jasminine and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Sulfamic acid-catalyzed multicomponent synthesis of 7-phenyl-7,12 dihydrobenzo(h)pyrido[2,3-b]naphthydrin-6(5H)-one derivatives: a green avenue

Loading next page...
 
/lp/springer_journal/sulfamic-acid-catalyzed-multicomponent-synthesis-of-7-phenyl-7-12-H02bVoo5na
Publisher
Springer Netherlands
Copyright
Copyright © 2016 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-016-2778-2
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial