Ann Hematol (2017) 96:1771–1772 DOI 10.1007/s00277-017-3080-0 LETTER TO THE EDITOR Sudden blindness as an initial manifestation of localized fusariosis in ethmoid sinus and optic nerve 1 1 2 3 Shuhei Kurosawa & Noriko Doki & Noritaka Sekiya & Syuzo Ikuta & 3 1 Yasunobu Takaki & Kazuteru Ohashi Received: 20 June 2017 /Accepted: 23 July 2017 /Published online: 27 July 2017 Springer-Verlag GmbH Germany 2017 Dear Editor, cutaneous lesions were noted at the time. Although mi- Reported cases of fusariosis in hematological malignan- crobiological examination of nasal discharge revealed cies are increasing [1–5]; however, blindness as an ini- Fusarium species, additional examinations including tial manifestation of neuro-invasive fusariosis is ex- whole body computed tomography scanning, blood cul- tremely rare. We herein report a unique case with ture or serological examination for fungal infection myelodysplastic syndrome (MDS) who demonstrated disclosed no evidence of generalized infection. Thus, sudden blindness resulting from localized fusariosis in the patient was diagnosed as localized fusariosis in eth- ethmoid sinus and optic nerve. moid sinus and optic nerve. The patient was orally ad- A 75-year-old female with MDS had been regularly ministered 400 mg/day voriconazole (VRCZ) for followed with oral prednisolone for the treatment of 2
Annals of Hematology – Springer Journals
Published: Jul 27, 2017
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