Sublocalizing the centromeric region in linkage groups from three metacentric rat chromosomes by FISH

Sublocalizing the centromeric region in linkage groups from three metacentric rat chromosomes by... Mammalian Genome 9, 479–481 (1998). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1998 Sublocalizing the centromeric region in linkage groups from three metacentric rat chromosomes by FISH Maria Larsson,* Eva Asp,* Åsa Johansson,* Xu Chun Lu ¨ , Dan Ro ¨ hme, Go ¨ ran Levan Department of Genetics, Go ¨ teborg University, Medicinareg 9C, S-413 90 Gothenburg, Sweden Received: 7 January 1998 / Accepted: 17 February 1998 Traditionally, the mouse has been the rodent of choice for genetic (D14Mgh2), P31-H6 (D14Mit4), P443-D3 (D15Mgh1), P202-F8 experimentation, and this research has generated a large amount of (D15Mgh2), and P219-G4 (D16Mit3). mapping data in the mouse. As the focus of interest moves from For Chr 16 two additional probes were used in the FISH analy- monogenic diseases towards more complex disorders, the rat is sis. The first was a cDNA of the kallikrein 3 (Klk3) gene (Inoue et becoming more popular as a genetic model since much physiologi- al. 1989; Beaubien et al. 1991). This gene corresponds to the cal research on complex diseases has been performed in the rat. As polymorphic microsatellite marker D16Wox13 (Bihoreau et al. a consequence, many suitable rat models are available for complex 1997). The http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Sublocalizing the centromeric region in linkage groups from three metacentric rat chromosomes by FISH

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Publisher
Springer-Verlag
Copyright
Copyright © 1998 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900802
Publisher site
See Article on Publisher Site

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