STUDY ON THE BEST INITIAL PROCESSING
TECHNOLOGY OF GASTRODIA ELATA
and Gangliang Huang
Original article submitted August 11, 2017.
The effects of different initial processing methods on the amount of gastrodin and gastrodigenin isolated from
Gastrodia elata Blume were investigated and the best initial processing technology was optimized. The con
tents of gastrodin and gastrodigenin were analyzed by high performance liquid chromatography (HPLC). It is
established that G. elata boiling in water followed by ethanol extraction is the best initial processing technol
ogy, which can provide the basis and reference for the standardized processing of G. elata herbs.
Keywords: Gastrodia elata Blume; initial processing technology; gastrodin; gastrodigenin; optimization.
Gastrodia elata Blume is the subterranean dried tuber of
perennial herbaceous plant of Orchidaceae family , which
is mainly produced in Shanxi, Yunnan, Guizhou, and other
places in China. The plant of G. elata has always been a hot
issue of traditional Chinese medicine research. Its main com-
ponents are gastrodin, gastrodigenin and other phenolic
compounds, sterols, nucleosides, organic acids, and polysac-
charides . Gastrodin and gastrodigenin are the main active
ingredients of G. elata  having specific pharmacological
activities, which allow their use as medicines . Gastrodin
produces sedative, anticonvulsant, analgesic and hypnotic ef-
fects . Gastrodigenin has the same analgesic effect as
gastrodin . At present, selection of the best method of G.
elata processing is based on the determination of gastrodin
content [2, 6].
Pharmaceutical Chemistry Journal, Vol. 52, No. 3, June, 2018 (Russian Original Vol. 52, No. 3, March, 2018)
0091-150X/18/5203-0224 © 2018 Springer Science+Business Media, LLC
Active Carbohydrate Research Center, Chongqing Normal University,
Chongqing, 401331 China.
Fig. 1. Chromatogram of gastrodin control (21.785 mg/mL).