Study of the Drosophila melanogaster trf2 gene and its protein product

Study of the Drosophila melanogaster trf2 gene and its protein product The Drosophila melanogaster TRF2 protein regulates transcription of several genes. The trf2 gene structure was studied. The gene proved to code for two protein isoforms, a known 75-kDa isoform and a newly identified 175-kDa isoform. The new isoform combines the known isoform sequence with an extended N end containing a coiled-coil motif. The long TRF2 isoform was found to act as a component of a multiprotein complex, including ISWI ATPase as well. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Study of the Drosophila melanogaster trf2 gene and its protein product

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Publisher
SP MAIK Nauka/Interperiodica
Copyright
Copyright © 2008 by Pleiades Publishing, Ltd.
Subject
Biomedicine; Microbial Genetics and Genomics; Human Genetics ; Animal Genetics and Genomics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1134/S1022795408020026
Publisher site
See Article on Publisher Site

Abstract

The Drosophila melanogaster TRF2 protein regulates transcription of several genes. The trf2 gene structure was studied. The gene proved to code for two protein isoforms, a known 75-kDa isoform and a newly identified 175-kDa isoform. The new isoform combines the known isoform sequence with an extended N end containing a coiled-coil motif. The long TRF2 isoform was found to act as a component of a multiprotein complex, including ISWI ATPase as well.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Mar 25, 2011

References

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