Study of regeneration in amphibians in age of molecular-genetic approaches and methods

Study of regeneration in amphibians in age of molecular-genetic approaches and methods The results of molecular-genetic mechanisms of regeneration in amphibians are reviewed. Based on the examples of traditional and well-studied models of the restoration of the retinas and lenses of eyes, as well as limbs and tails in amphibians, we analyze the current state of regeneration problems and questions linked to cell reprogramming, growth, and morphogenesis. The development of the Kol’tsov school of thought in the age of molecular-genetic approaches and methods are monitored. The contemporary interpretation of organ regeneration in terms of molecular-genetic regulation and a new look at the definition of regeneration as repeated development is proposed. We also emphasize the current problems that exist in that field of developmental biology and are caused by the many difficulties of genome sequencing and the introduction of transgenesis in Urodela, the animal species with the highest regeneration abilities. Russian Journal of Genetics Springer Journals

Study of regeneration in amphibians in age of molecular-genetic approaches and methods

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SP MAIK Nauka/Interperiodica
Copyright © 2013 by Pleiades Publishing, Ltd.
Biomedicine; Human Genetics; Animal Genetics and Genomics; Microbial Genetics and Genomics
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