Structural and functional organization of centromeres in plant chromosomes

Structural and functional organization of centromeres in plant chromosomes The centromere is a specific chromosomal locus that forms the protein complex and kinetochore, maintains sister chromatid cohesion, controls chromosome attachment to the spindle, and coordinates chromosome movement during mitosis and meiosis. Defective centromere assembly or its dysfunction causes cell cycle arrest, structural abnormalities of the chromosomes, and aneuploidy. This review collects the data on the structure, functions, and epigenetic modification of centromeric chromatin, the structure and functions of the kinetochore, and sister chromatid cohesion. Taken together, these data provide insight into the specific architecture and functioning of the centromere during chromosome division and segregation in plants. Russian Journal of Genetics Springer Journals

Structural and functional organization of centromeres in plant chromosomes

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Pleiades Publishing
Copyright © 2014 by Pleiades Publishing, Inc.
Biomedicine; Human Genetics; Animal Genetics and Genomics; Microbial Genetics and Genomics
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