Strengthening Instrumental Variables Through Weighting

Strengthening Instrumental Variables Through Weighting Instrumental variable (IV) methods are widely used to deal with the issue of unmeasured confounding and are becoming popular in health and medical research. IV models are able to obtain consistent estimates in the presence of unmeasured confounding, but rely on assumptions that are hard to verify and often criticized. An instrument is a variable that influences or encourages individuals toward a particular treatment without directly affecting the outcome. Estimates obtained using instruments with a weak influence over the treatment are known to have larger small-sample bias and to be less robust to the critical IV assumption that the instrument is randomly assigned. In this work, we propose a weighting procedure for strengthening the instrument while matching. Through simulations, weighting is shown to strengthen the instrument and improve robustness of resulting estimates. Unlike existing methods, weighting is shown to increase instrument strength without compromising match quality. We illustrate the method in a study comparing mortality between kidney dialysis patients receiving hemodialysis or peritoneal dialysis as treatment for end-stage renal disease. Statistics in Biosciences Springer Journals

Strengthening Instrumental Variables Through Weighting

Loading next page...
Springer US
Copyright © 2016 by International Chinese Statistical Association
Statistics; Statistics for Life Sciences, Medicine, Health Sciences; Biostatistics; Theoretical Ecology/Statistics
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial