Stereoselective synthesis of heterocyclic compounds

Stereoselective synthesis of heterocyclic compounds DOI 10.1007/s10593-018-2278-y Chemistry of Heterocyclic Compounds 2018, 54(4), 379 FROM THE EDITOR Stereoselective synthesis of heterocyclic compounds Heterocycles are ubiquitous in several areas of chemical sciences spanning from materials to natural products and pharmaceuticals. It is not an overstatement to say that heterocyclic compounds affect our daily life. For these reasons, the chemistry of heterocycles is still a fertile land explored by synthetic chemists worldwide. Researchers from an important pharmaceutical company in a recent review (Org. Biomol. Chem. 2016, 14, 6611) listed the opportunities for new methodology development in hetero- cyclic chemistry. Among the challenges to be addressed in developing new methodologies, the authors mentioned the regio-, stereo-, and chemoselective synthesis of hetero- cycles, as well as their functionalization. Concerning the reaction conditions, it was stated that modern synthesis This thematic issue, consisting of two reviews articles, would be focused on the use of cheap and less hazardous three microreviews ("Heterocycles in focus''), nine original reagents, wide tolerance to functional groups, and stream- articles, and two short communications, encompasses lined processes. Thus, the stereocontrol in the synthesis and several aspects of the modern synthesis of heterocycles. functionalization of heterocycles remains a hot topic and a I really hope the readers find inspiration for future work by demanding task in modern heterocyclic chemistry. Some looking at this issue of "Chemistry of Heterocyclic Com- top seller drugs such as sofosbuvir, for treatment of pounds". As guest editor of this issue, I would like to thank hepatitis C, rivaroxaban, for treatment of venous thrombo- all the authors for accepting the invitation to be on board in embolism, efavirenz and emtricitabine, for treatment of this endeavor. I am grateful to the Editorial Office and in HIV infection, witness the relevance of the stereoselective particular to Dr. Andris Amoliņš for professional support preparation of heterocyclic compounds. With this premise, and assistance during the preparation of the thematic issue. the thematic issue ''Stereoselective synthesis of hetero- cyclic compounds'', far from to be exhaustive, was intended to provide a snapshot of recent progress in the field of stereoselective preparation and characterization of hetero- cycles. Guest Editor of the thematic issue Professor Renzo Luisi University of Bari Aldo Moro, Italy 0009-3122/18/54(4)-0379©2018 Springer Science+Business Media, LLC http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chemistry of Heterocyclic Compounds Springer Journals

Stereoselective synthesis of heterocyclic compounds

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Chemistry; Organic Chemistry; Pharmacy
ISSN
0009-3122
eISSN
1573-8353
D.O.I.
10.1007/s10593-018-2278-y
Publisher site
See Article on Publisher Site

Abstract

DOI 10.1007/s10593-018-2278-y Chemistry of Heterocyclic Compounds 2018, 54(4), 379 FROM THE EDITOR Stereoselective synthesis of heterocyclic compounds Heterocycles are ubiquitous in several areas of chemical sciences spanning from materials to natural products and pharmaceuticals. It is not an overstatement to say that heterocyclic compounds affect our daily life. For these reasons, the chemistry of heterocycles is still a fertile land explored by synthetic chemists worldwide. Researchers from an important pharmaceutical company in a recent review (Org. Biomol. Chem. 2016, 14, 6611) listed the opportunities for new methodology development in hetero- cyclic chemistry. Among the challenges to be addressed in developing new methodologies, the authors mentioned the regio-, stereo-, and chemoselective synthesis of hetero- cycles, as well as their functionalization. Concerning the reaction conditions, it was stated that modern synthesis This thematic issue, consisting of two reviews articles, would be focused on the use of cheap and less hazardous three microreviews ("Heterocycles in focus''), nine original reagents, wide tolerance to functional groups, and stream- articles, and two short communications, encompasses lined processes. Thus, the stereocontrol in the synthesis and several aspects of the modern synthesis of heterocycles. functionalization of heterocycles remains a hot topic and a I really hope the readers find inspiration for future work by demanding task in modern heterocyclic chemistry. Some looking at this issue of "Chemistry of Heterocyclic Com- top seller drugs such as sofosbuvir, for treatment of pounds". As guest editor of this issue, I would like to thank hepatitis C, rivaroxaban, for treatment of venous thrombo- all the authors for accepting the invitation to be on board in embolism, efavirenz and emtricitabine, for treatment of this endeavor. I am grateful to the Editorial Office and in HIV infection, witness the relevance of the stereoselective particular to Dr. Andris Amoliņš for professional support preparation of heterocyclic compounds. With this premise, and assistance during the preparation of the thematic issue. the thematic issue ''Stereoselective synthesis of hetero- cyclic compounds'', far from to be exhaustive, was intended to provide a snapshot of recent progress in the field of stereoselective preparation and characterization of hetero- cycles. Guest Editor of the thematic issue Professor Renzo Luisi University of Bari Aldo Moro, Italy 0009-3122/18/54(4)-0379©2018 Springer Science+Business Media, LLC

Journal

Chemistry of Heterocyclic CompoundsSpringer Journals

Published: Jun 7, 2018

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