Stereo-selective green protocol for the synthesis of highly substituted 1-phenyl-tetrahydro indeno [1, 2-b]pyrroles

Stereo-selective green protocol for the synthesis of highly substituted 1-phenyl-tetrahydro... Electronic supplementary material The online version of this article (doi:10.1007/s11164-017-2893-8) contains supplementary material, which is available to authorized users. & Vediappen Padmini Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, Tamilnadu 625021, India X-ray Diffraction Laboratory, Department of Chemistry, Texas A&M University, College Station, TX 77842, USA 123 4518 M. Kumar et al. Keywords Multicomponent reactions  Green  Stereo-selective  Substituted 1-phenyl-tetrahydro indeno [1, 2-b]pyrroles Introduction Indenopyrroles [1–3] represent one of the most important classes of five membered nitrogen containing heterocyclic compounds largely present in natural and synthetic organic compounds [4, 5] with pharmacological [6, 7] and material science application [8, 9]. The best known natural pyrroles are the heme derivatives [10], chlorophyll [11] and alkaloids [12–15] etc. Polycyclic fused pyrroles [6, 16–19] are the most ever-present heterocyclics in nature and employed as versatile building blocks in synthetic organic chemistry [20]. So the researchers are devoted to finding new indenopyrroles [21–23] and their motifs. MCRs [24] play an important role in efficient synthesis when compared to other available methods [25–27]. A pyrrole unit can be found in many drugs [28]. In spite of a variety of synthetic methodology for indenopyrroles [29], the classical Knorr Research on Chemical Intermediates Springer Journals

Stereo-selective green protocol for the synthesis of highly substituted 1-phenyl-tetrahydro indeno [1, 2-b]pyrroles

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Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
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