Ann Surg Oncol (2017) 24:2556–2562 DOI 10.1245/s10434-017-5898-z OR IG INA L A R TIC L E – BREA S T O NC OLOG Y Standard Pathologic Features Can Be Used to Identify a Subset of Estrogen Receptor-Positive, HER2 Negative Patients Likely to Beneﬁt from Neoadjuvant Chemotherapy 1 1 2 1 Oriana A. Petruolo, MD , Melissa Pilewskie, MD , Sujata Patil, PhD , Andrea V. Barrio, MD , Michelle Stempel, 1 3 1 MPH , Hannah Y. Wen, MD, PhD , and Monica Morrow, MD 1 2 Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY ; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY ABSTRACT axilla, nodal pCR among cN? patients (n = 301) ranged Background. The beneﬁt of neoadjuvant chemotherapy from 0 to 35% (p \ 0.0001) within these groups, and was (NAC) in patients with estrogen receptor-positive (ER?)/ most frequent in PR-/HP patients. human epidermal growth factor receptor 2-negative Conclusions. ER?/HER2- patients most likely to beneﬁt (HER2-) breast cancers and in invasive lobular carcinoma from NAC are those with PR- and HP tumors. Patients (ILC) is
Annals of Surgical Oncology – Springer Journals
Published: May 30, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera