Sporadic Creutzfeldt-Jakob disease presenting with isolated progressive non-fluent aphasia in a young woman

Sporadic Creutzfeldt-Jakob disease presenting with isolated progressive non-fluent aphasia in a... Neurol Sci (2017) 38:1535–1537 DOI 10.1007/s10072-017-2968-8 LETTER TO THE EDITOR Sporadic Creutzfeldt-Jakob disease presenting with isolated progressive non-fluent aphasia in a young woman 1 1 2 1 Alberto Terrin & Andrea Barp & Gianluigi Zanusso & Paolo Gallo & Annachiara Cagnin Received: 20 February 2017 /Accepted: 18 April 2017 /Published online: 25 April 2017 Springer-Verlag Italia 2017 Introduction Probable sCJD was diagnosed in vivo with detection of prion protein (PrP) seeding activity through Real-Time Quaking- Creutzfeldt-Jakob disease (CJD) belongs to a family of neu- Induced Conversion (RT-QuIC) in CSF and olfactory mucosa rodegenerative diseases known as transmissible spongiform (OM) samples. encephalopathies or prion diseases. Sporadic (sCJD), the most common form, occurs at an incidence of 1/100.0000/year. Onset usually occurs in the seventh decade of life, and life Case report expectancy is about 5 months. Clinically, sCJD is character- ized by a rapidly progressive dementia, myoclonus, visual, or A 47-year-old woman was admitted to the Neurological cerebellar disturbances, pyramidal or extrapyramidal signs, Clinic, Department of Neurosciences, in Padova (Italy) for and akinetic mutism [1]. Brain MRI can support the clinical rapidly progressive language impairment in the previous diagnosis of sCJD showing signal hyperintensity at the month. At admission, neurological evaluation http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neurological Sciences Springer Journals

Sporadic Creutzfeldt-Jakob disease presenting with isolated progressive non-fluent aphasia in a young woman

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Publisher
Springer Milan
Copyright
Copyright © 2017 by Springer-Verlag Italia
Subject
Medicine & Public Health; Neurology; Neuroradiology; Neurosurgery; Psychiatry
ISSN
1590-1874
eISSN
1590-3478
D.O.I.
10.1007/s10072-017-2968-8
Publisher site
See Article on Publisher Site

Abstract

Neurol Sci (2017) 38:1535–1537 DOI 10.1007/s10072-017-2968-8 LETTER TO THE EDITOR Sporadic Creutzfeldt-Jakob disease presenting with isolated progressive non-fluent aphasia in a young woman 1 1 2 1 Alberto Terrin & Andrea Barp & Gianluigi Zanusso & Paolo Gallo & Annachiara Cagnin Received: 20 February 2017 /Accepted: 18 April 2017 /Published online: 25 April 2017 Springer-Verlag Italia 2017 Introduction Probable sCJD was diagnosed in vivo with detection of prion protein (PrP) seeding activity through Real-Time Quaking- Creutzfeldt-Jakob disease (CJD) belongs to a family of neu- Induced Conversion (RT-QuIC) in CSF and olfactory mucosa rodegenerative diseases known as transmissible spongiform (OM) samples. encephalopathies or prion diseases. Sporadic (sCJD), the most common form, occurs at an incidence of 1/100.0000/year. Onset usually occurs in the seventh decade of life, and life Case report expectancy is about 5 months. Clinically, sCJD is character- ized by a rapidly progressive dementia, myoclonus, visual, or A 47-year-old woman was admitted to the Neurological cerebellar disturbances, pyramidal or extrapyramidal signs, Clinic, Department of Neurosciences, in Padova (Italy) for and akinetic mutism [1]. Brain MRI can support the clinical rapidly progressive language impairment in the previous diagnosis of sCJD showing signal hyperintensity at the month. At admission, neurological evaluation

Journal

Neurological SciencesSpringer Journals

Published: Apr 25, 2017

References

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