Access the full text.
Sign up today, get DeepDyve free for 14 days.
Y. Batra, S. Rakesh, N. Panda, V. Lokesh, R. Subramanyam (2010)
Intrathecal clonidine decreases propofol sedation requirements during spinal anesthesia in infantsPediatric Anesthesia, 20
G Frawley, G Bell, N Disma, DE Withington, JC Graaff, NS Morton, ME McCann, SJ Arnup, O Bagshaw, A Wolfler, D Bellinger, AJ Davidson (2015)
General anesthesia compared to spinal anesthesia (GAS) consortium. Predictors of failure of awake regional anesthesia for neonatal hernia repair: data from the general anesthesia compared to spinal anesthesia study—comparing apnea and neurodevelopmental outcomesAnesthesiology, 123
A. Rochette, R. Troncin, O. Raux, C. Dadure, J. Lubrano, É. Barbotte, X. Capdevila (2005)
Clonidine added to bupivacaine in neonatal spinal anesthesia: a prospective comparison in 124 preterm and term infantsPediatric Anesthesia, 15
YK Batra, SV Rakesh, NB Panda, VC Lokesh, R Subramanyam (2010)
Intrathecal clonidine decreases propofol sedation requirements during spinal anesthesia in infantsPaediatr Anaesth, 20
L. Kachko, E. Simhi, E. Tzeitlin, R. Efrat, E. Tarabikin, E. Peled, Iulia Metzner, J. Katz (2007)
Spinal anesthesia in neonates and infants – a single‐center experience of 505 casesPediatric Anesthesia, 17
M. Ratajczak-Enselme, J. Estebe, F-X Rose, E. Wodey, J. Malinovsky, F. Chevanne, G. Dollo, C. Ecoffey, P. Corre (2007)
Effect of epinephrine on epidural, intrathecal, and plasma pharmacokinetics of ropivacaine and bupivacaine in sheep.British journal of anaesthesia, 99 6
Keane Tzong, Sena Han, A. Roh, C. Ing (2012)
Epidemiology of Pediatric Surgical Admissions in US Children: Data From the HCUP Kids Inpatient DatabaseJournal of Neurosurgical Anesthesiology, 24
A Rochette, R Troncin, O Raux, C Dadure, JF Lubrano, E Barbotte, X Capdevila (2005)
Clonidine added to bupivacaine in neonatal spinal anesthesia: a prospective comparison in 124 preterm and term infantsPaediatr Anaesth, 15
L Kachko, E Birk, E Simhi, E Tzeitlin, E Freud, J Katz (2012)
Spinal anesthesia for noncardiac surgery in infants with congenital heart diseasesPaediatr Anaesth, 22
Y. Batra, V. Lokesh, N. Panda, S. Rajeev, K. Rao (2008)
Dose–response study of intrathecal fentanyl added to bupivacaine in infants undergoing lower abdominal and urologic surgeryPediatric Anesthesia, 18
L Kachko, E Simhi, E Tzeitlin, R Efrat, E Tarabikin, E Peled, I Metzner, J Katz (2007)
Spinal anesthesia in neonates and infants—a single-center experience of 505 casesPaediatr Anaesth, 17
The (cid:1) 2 -Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects
E. Whitaker, B. Wiemann, D. DaJusta, S. Alpert, C. Ching, D. McLeod, J. Tobias, V. Jayanthi (2017)
Spinal anesthesia for pediatric urological surgery: Reducing the theoretic neurotoxic effects of general anesthesia.Journal of pediatric urology, 13 4
Abajian Jc, Mellish Rw, Brown Af, Perkins Fm, Lambert Dh, J. Mazuzan (1984)
Spinal anesthesia for surgery in the high-risk infant.Anesthesia and analgesia, 63 3
L. Kachko, E. Simhi, E. Freud, E. Dlugy, J. Katz (2009)
Impact of spinal anesthesia for open pyloromyotomy on operating room time.Journal of pediatric surgery, 44 10
Robert Williams, David Adams, Eva Aladjem, J. Kreutz, K. Sartorelli, Dennis Vane, J. Abajian (2006)
The Safety and Efficacy of Spinal Anesthesia for Surgery in Infants: The Vermont Infant Spinal RegistryAnesthesia & Analgesia, 102
A. Lambertz, G. Schälte, J. Winter, A. Röth, D. Busch, T. Ulmer, G. Steinau, U. Neumann, C. Klink (2014)
Spinal anesthesia for inguinal hernia repair in infants: a feasible and safe method even in emergency casesPediatric Surgery International, 30
H. Kokki (2012)
Spinal blocksPediatric Anesthesia, 22
Xin Wang, Zheng Xu, C. Miao (2014)
Current Clinical Evidence on the Effect of General Anesthesia on Neurodevelopment in Children: An Updated Systematic Review with Meta-RegressionPLoS ONE, 9
H Kokki (2012)
Spinal blocksPaediatr Anaesth, 22
T López, FJ Sánchez, JC Garzón, C Muriel (2012)
Spinal anesthesia in pediatric patientsMin Anestesiol, 78
A. Rochette, O. Raux, R. Troncin, C. Dadure, R. Verdier, X. Capdevila (2004)
Clonidine Prolongs Spinal Anesthesia in Newborns: A Prospective Dose-Ranging StudyAnesthesia & Analgesia, 98
L. Kachko, E. Birk, E. Simhi, E. Tzeitlin, E. Freud, J. Katz (2012)
Spinal anesthesia for noncardiac surgery in infants with congenital heart diseasesPediatric Anesthesia, 22
J. Eisenach, M. Kock, W. Klimscha (1996)
Alpha sub 2 -Adrenergic Agonists for Regional Anesthesia: A Clinical Review of Clonidine (1984 - 1995)Anesthesiology, 85
G. Frawley, G. Bell, N. Disma, D. Withington, J. Graaff, N. Morton, M. McCann, S. Arnup, O. Bagshaw, A. Wolfler, D. Bellinger, A. Davidson (2015)
Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair: Data from the General Anesthesia Compared to Spinal Anesthesia Study—Comparing Apnea and Neurodevelopmental OutcomesAnesthesiology, 123
C. Ing, Lena Sun, Alexander Friend, A. Roh, Susan Lei, H. Andrews, Guohua Li, Robert Williams (2016)
Adverse Events and Resource Utilization After Spinal and General Anesthesia in Infants Undergoing PyloromyotomyRegional Anesthesia & Pain Medicine, 41
Purpose Spinal anesthesia (SA) is being increasingly used in infants to avoid the potential negative neurocognitive effects of general anesthesia (GA). However, SA has been reported to provide a relatively short duration of surgical anesthesia. Methods We retrospectively reviewed SA cases for surgical procedures lasting more than 60 min in children up to 3 years old. All patients received bupivacaine 0.5% (1 mg/kg up to 7 mg) with clonidine 1 µg/kg ± epinephrine. The primary outcome was success of SA without subsequent conversion to GA. Results Thirty-five patients met inclusion criteria (all males, age 7 ± 5 months, weight 8 ± 2 kg). Procedures included male genital, groin and multiple site surgeries. Average surgical duration was 71 ± 12 min (range 60–111 min). SA was successful in 31 of 35 patients (89%; 95% confidence interval 78, 99%). The cause of failure was rarely due to the duration of surgery (1 of 4 patients). Six patients with successful SA required sedation with dexmedetomidine ± fentanyl. Differences in procedure duration and patient characteristics were not statistically significant between successful and failed SA. Conclusions SA is a highly successful technique and may offer an alternative to GA in children undergoing appropriate surgery expected to last as long as 60–100 min. Keywords
Journal of Anesthesia – Springer Journals
Published: May 28, 2018
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.